DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15253 and nas-28

DIOPT Version :9

Sequence 1:	NP_609758.1	Gene:	CG15253 / 34916	FlyBaseID:	FBgn0028948	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_498342.3	Gene:	nas-28 / 185658	WormBaseID:	WBGene00003546	Length:	497	Species:	Caenorhabditis elegans

Alignment Length:	208	Identity:	74/208 - (35%)
Similarity:	109/208 - (52%)	Gaps:	11/208 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 SSRNIWRNETYRWPNRI-IYYHINSYIDEEHRNHIVSAIQKIESISCLTFKEATTDQKYYVNVTS 108
            |.|....:.|..|...: |:|..::.:...:..::..|||.....|||:|||....:...  ..|
Worm   118 SKRQAIVDTTNFWSVSVPIFYQFDTKLSATNIANVRKAIQFWNDNSCLSFKEDNNAKNRL--FLS 180

  Fly   109 EEGGCFSYIGYLNRVQQLNLQNNEIGVG--CFRLYTIVHEFLHALGFFHQQSAADRDDYVQIVEE 171
            ..|||:||:|     :|:::....:.||  |....|..||.:||:||:||||.||||:||.:...
Worm   181 SAGGCWSYVG-----KQVDMPYQMVSVGPNCDTFGTATHELMHAIGFWHQQSRADRDNYVYVDFS 240

  Fly   172 NITEGMEFNFDKYTEETVNDFGEKYDYGSVMHYGPYAFSKNGER-TILALEEGKEDVIGQRLELS 235
            ||.....:||.|...:........|||||||.|.||||:.:..: ||||.|.|.::.:|||...:
Worm   241 NIIPSQAYNFQKMAVDQAQLLNLPYDYGSVMQYYPYAFAVDSSKYTILAKENGFQNSMGQREAPA 305

  Fly   236 ETDIRKLNAIYKC 248
            .:||..:|.:|.|
Worm   306 FSDIIGVNKLYNC 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15253	NP_609758.1	Astacin	55..250	CDD:279708	71/198 (36%)
CG15253	NP_609758.1	ZnMc_astacin_like	59..246	CDD:239807	68/190 (36%)
nas-28	NP_498342.3	Astacin	135..320	CDD:279708	70/191 (37%)
		ZnMc_astacin_like	135..316	CDD:239807	68/187 (36%)
		CUB	393..480	CDD:214483
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920