DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15253 and nas-4

DIOPT Version :9

Sequence 1:	NP_609758.1	Gene:	CG15253 / 34916	FlyBaseID:	FBgn0028948	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001254938.1	Gene:	nas-4 / 182259	WormBaseID:	WBGene00003523	Length:	365	Species:	Caenorhabditis elegans

Alignment Length:	240	Identity:	84/240 - (35%)
Similarity:	139/240 - (57%)	Gaps:	19/240 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 IRIETDPELTAGYIEGDMVPSGSSRNIWRN---------ETY-RWPNRIIYYHINSYIDEEHRNH 77
            |:::.||.: ..|.|||::.....:.:..|         :.| ||||..|.|.::|......|:.
Worm    61 IKVKDDPTI-GNYSEGDILLESPKKFVEENNKLGRNAIKQIYRRWPNNEIPYTLSSQYGSYARSV 124

  Fly    78 IVSAIQKIESISCLTFKEATTDQKY-YVNVTSEEGGCFSYIGYLNRVQQLNLQNNEIGVGCFRLY 141
            |.:|:.:..:.:|:.|......:.: |:.:..:| ||:|.:|.....|.::|.:     ||.::.
Worm   125 IANAMNEYHTKTCVKFVARDPSKHHDYLWIHPDE-GCYSLVGKTGGKQPVSLDS-----GCIQVG 183

  Fly   142 TIVHEFLHALGFFHQQSAADRDDYVQIVEENITEGMEFNFDKYTEETVNDFGEKYDYGSVMHYGP 206
            |||||.:||:||||:||..|||.|:.:|.:|:..|.:..|:||....::...|.|||.|:|||||
Worm   184 TIVHELMHAVGFFHEQSRQDRDSYIDVVWQNVMNGADDQFEKYNLNVISHLDEPYDYASIMHYGP 248

  Fly   207 YAFSKNGERTILALEEGKEDVIGQRLELSETDIRKLNAIYKCPTV 251
            ||||.:|::|::..:.|.|. :|||::.|:.|:||:|.:|.||.|
Worm   249 YAFSGSGKKTLVPKKSGSER-MGQRVKFSDIDVRKINKLYNCPGV 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15253	NP_609758.1	Astacin	55..250	CDD:279708	74/196 (38%)
CG15253	NP_609758.1	ZnMc_astacin_like	59..246	CDD:239807	68/187 (36%)
nas-4	NP_001254938.1	Astacin	102..290	CDD:279708	72/194 (37%)
nas-4	NP_001254938.1	ZnMc_astacin_like	106..287	CDD:239807	68/187 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49330
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.930