DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15253 and nas-6

DIOPT Version :9

Sequence 1:	NP_609758.1	Gene:	CG15253 / 34916	FlyBaseID:	FBgn0028948	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001040902.1	Gene:	nas-6 / 181796	WormBaseID:	WBGene00003525	Length:	344	Species:	Caenorhabditis elegans

Alignment Length:	280	Identity:	92/280 - (32%)
Similarity:	139/280 - (49%)	Gaps:	37/280 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MCYYSILLLLLVVVNVAWAAPSI--------RIETDPELT------AGYIEGDM---------VP 42
            |..:.:||...:|..|..:.||.        .|..|..:|      :|..:||:         :|
Worm     1 MLDHVLLLTYCLVSTVVRSQPSADVFRSFAGYIPEDHRVTHHEWQNSGKFQGDIDGVDPNLLKLP 65

  Fly    43 SGSSR-NIWRNETYRWPNRIIYYHINSYIDEEHRNHIVSAIQKIESISCLTF--KEATTDQKYYV 104
            .|... |..:|:...|...:|.|.:::.........:..|.......:|:.|  :|..||   |:
Worm    66 EGPVLFNALKNKQLTWEGGVIPYEMDTAFSPNEIKILEKAFDSYRRTTCIRFEKREGQTD---YL 127

  Fly   105 NVTSEEG-GCFSYIGYLNRVQQLNLQNNEIGVGCFRLYTIVHEFLHALGFFHQQSAADRDDYVQI 168
            |:.  :| ||:|.:|.....|:::|     |.|||....||||.:|::||:|:.|.|||||:::|
Worm   128 NIV--KGYGCYSQVGRTGGKQEISL-----GRGCFFHEIIVHELMHSVGFWHEHSRADRDDHIKI 185

  Fly   169 VEENITEGMEFNFDKYTEETVNDFGEKYDYGSVMHYGPYAFSKNGERTILALEEGKEDVIGQRLE 233
            ..:||..||:..|||.:....:..||.|||.|:|||...|||:||..||..:|.|...|||..::
Worm   186 NWDNILPGMKSQFDKISAVLQDLQGENYDYKSIMHYDSTAFSRNGRNTIETVENGFTQVIGTAMD 250

  Fly   234 LSETDIRKLNAIYKCPTVKE 253
            ||..||.|:|.:|.|.|.|:
Worm   251 LSPLDIVKINKLYSCKTKKK 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15253	NP_609758.1	Astacin	55..250	CDD:279708	73/197 (37%)
CG15253	NP_609758.1	ZnMc_astacin_like	59..246	CDD:239807	70/189 (37%)
nas-6	NP_001040902.1	Astacin	80..265	CDD:279708	72/194 (37%)
		ZnMc_astacin_like	83..263	CDD:239807	70/189 (37%)
		ShK	299..334	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_112325
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920