DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15253 and nas-9

DIOPT Version :9

Sequence 1:	NP_609758.1	Gene:	CG15253 / 34916	FlyBaseID:	FBgn0028948	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_741532.1	Gene:	nas-9 / 178875	WormBaseID:	WBGene00003528	Length:	546	Species:	Caenorhabditis elegans

Alignment Length:	238	Identity:	66/238 - (27%)
Similarity:	106/238 - (44%)	Gaps:	34/238 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 ELTAGYIEGDMVP-SG--------SSRNIWRNETYRWPNRIIYYHINSYIDEEHRNHIVSAIQKI 85
            ::.||...|..|| ||        ...:||:.         |.|.::..::|..:..|..|:.:|
Worm   287 DVGAGGGGGGRVPRSGVFFQESAVQKWDIWKP---------IQYTLDDSLEESDKKDIRDALHEI 342

  Fly    86 ESISCLTFKEATTDQKYYVNVTSEEGGCFSYIGYLNRVQ-----QLNLQ-NNEIGVGCFRLYTIV 144
            ...:|:.|:...|.:.|::|....:...|..:.|:.|..     .|:.| .:..||.       :
Worm   343 SINTCILFRYNATPKGYHLNYMKVDSTTFCGLSYVGRTDPANPIYLSFQCGDNRGVA-------M 400

  Fly   145 HEFLHALGFFHQQSAADRDDYVQIVEENITEGMEFNFDKYTEETVNDFGEKYDYGSVMHYGPYAF 209
            ||.:||||..||....|||.|::|...||.......|.....:....:|.||.|.|:|||..|..
Worm   401 HETMHALGVSHQHLRLDRDKYIKIDWSNIDPQHYDTFAISDAKLYTSYGTKYAYDSIMHYNAYLG 465

  Fly   210 SKNGER-TILALEEGKEDV--IGQRLELSETDIRKLNAIYKCP 249
            :|:..: |::.|...:|:.  :|||.:|:..|||.|..:|..|
Worm   466 AKDPNKPTMIPLVNPQENTPKLGQRAKLTRGDIRLLKKMYCRP 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15253	NP_609758.1	Astacin	55..250	CDD:279708	57/204 (28%)
CG15253	NP_609758.1	ZnMc_astacin_like	59..246	CDD:239807	55/195 (28%)
nas-9	NP_741532.1	Astacin	311..505	CDD:279708	57/209 (27%)
		ZnMc_astacin_like	316..505	CDD:239807	56/204 (27%)
		ShKT	510..546	CDD:214586
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010