DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15253 and nas-36

DIOPT Version :9

Sequence 1:	NP_609758.1	Gene:	CG15253 / 34916	FlyBaseID:	FBgn0028948	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_492109.2	Gene:	nas-36 / 172506	WormBaseID:	WBGene00003552	Length:	617	Species:	Caenorhabditis elegans

Alignment Length:	211	Identity:	67/211 - (31%)
Similarity:	106/211 - (50%)	Gaps:	12/211 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 RNIWRNETYRWPNRIIYYHINSYIDEEHRNHIVSAIQKIESISCLTFKEAT-TDQKYYVNVTSEE 110
            |:...::|..|....|.|..:..||....:.|::||:..|..:|:||:..: :....|:...|.:
Worm   126 RSFVSDKTATWKTMPIKYRFHESIDFYTISQIIAAIRFWEDSTCITFENVSDSPDGDYIEFFSGQ 190

  Fly   111 GGCFSYIGYLNRVQQLNLQNNEIGVGCFRLYTIVHEFLHALGFFHQQSAADRDDYVQIVEENITE 175
             ||:|.||     :....|...||..|.::..|.||..||||.:|:||..|...||.|..:.|..
Worm   191 -GCYSMIG-----RNGGRQGISIGESCVKMGVIEHEIGHALGLWHEQSRPDALGYVTIERDFILP 249

  Fly   176 GMEFNFDKYTEETVNDFGEKYDYGSVMHYGPYAFSKNGE-RTILALEEGKEDVIGQRLELSETDI 239
            ....:|.:..:| ::..|..||.|||||||..|||.:.: :|::..:...:..||||.:||..|:
Worm   250 SYISDFLQRDDE-IDTLGIPYDLGSVMHYGSTAFSVDQKSKTVVTRDSLYQQTIGQREKLSFYDV 313

  Fly   240 RKLNAIY---KCPTVK 252
            ..:|..|   :|.:.|
Worm   314 ATINTAYCKDECKSEK 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15253	NP_609758.1	Astacin	55..250	CDD:279708	64/199 (32%)
CG15253	NP_609758.1	ZnMc_astacin_like	59..246	CDD:239807	61/188 (32%)
nas-36	NP_492109.2	Astacin	134..323	CDD:279708	63/195 (32%)
		ZnMc_astacin_like	140..320	CDD:239807	61/186 (33%)
		CUB	380..478	CDD:214483
		TSP1	510..556	CDD:214559
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820