DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15253 and astl3a.3

DIOPT Version :9

Sequence 1:	NP_609758.1	Gene:	CG15253 / 34916	FlyBaseID:	FBgn0028948	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_031746774.1	Gene:	astl3a.3 / 100498584	XenbaseID:	XB-GENE-22069675	Length:	529	Species:	Xenopus tropicalis

Alignment Length:	316	Identity:	100/316 - (31%)
Similarity:	141/316 - (44%)	Gaps:	84/316 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MCYYSILLLLLVVVNVAWAAPSIRI-------------------------ETDPELTAGYIEGDM 40
            |.:...::||..::..||..|:..|                         |.|...|.|.:.|..
Frog     3 MVHTKSIILLACIMGSAWTYPAQIIFPYQEMLEKDSLTNLDLLEALGKSAEKDALATEGTVRGME 67

  Fly    41 VP-----SGS----------SRNIWRNETYR------------------WPNR-----IIYYHIN 67
            :|     |||          :|.| |..||:                  ||..     |:.|:.:
Frog    68 MPVLGKKSGSVDVFTQISKVNRGI-RVPTYQGDILRPKGRSAMNCTECLWPKSTDGTVIVPYNFS 131

  Fly    68 SYIDEEHRNHIVSAIQKIESISCLTF--KEATTDQKYYVNVTSEEGGCFSYIGYLNRVQQLNLQN 130
            |....:......|.:|:.||::|:.|  :...||   ::::.| :.||.|::|.:...|.:.|.:
Frog   132 SNYSADQLALFKSTMQEYESLTCVRFVPRANETD---FLSIVS-DNGCASFLGKVGGDQTVQLDS 192

  Fly   131 NEIGVGCFRLYTIVHEFLHALGFFHQQSAADRDDYVQIVEENITEGMEFNFDKYTEETVNDFGEK 195
                .||.....|.||..|||||:|:||.:||||||.|..|||..|.|.||:|...   |:.|.:
Frog   193 ----YGCIYRGIIQHELNHALGFYHEQSRSDRDDYVTIHTENIIPGYEGNFNKADS---NNLGLE 250

  Fly   196 YDYGSVMHYGPYAFSKNGERTILALEEGKED---VIGQRLELSETDIRKLNAIYKC 248
            |||.|||||...||||||..||:.    |.|   .||||..||..|:.|:|.:|:|
Frog   251 YDYSSVMHYSGDAFSKNGNLTIVP----KPDPTVPIGQRDGLSILDVSKINRLYQC 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15253	NP_609758.1	Astacin	55..250	CDD:279708	80/222 (36%)
CG15253	NP_609758.1	ZnMc_astacin_like	59..246	CDD:239807	75/196 (38%)
astl3a.3	XP_031746774.1	ZnMc_hatching_enzyme	121..302	CDD:239810	76/195 (39%)
		CUB	306..414	CDD:238001
		CUB	419..527	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010