DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15253 and astl2d.5

DIOPT Version :9

Sequence 1:	NP_609758.1	Gene:	CG15253 / 34916	FlyBaseID:	FBgn0028948	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_031756347.1	Gene:	astl2d.5 / 100495579	XenbaseID:	XB-GENE-22069752	Length:	497	Species:	Xenopus tropicalis

Alignment Length:	229	Identity:	75/229 - (32%)
Similarity:	117/229 - (51%)	Gaps:	32/229 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 EGDMVPS-------GSSRN-------IWRNETYRWPNRIIY--YHINSYIDEEHRNHIVSAIQKI 85
            :|:.||.       |.||:       :|:.     .|..:|  |.::........|.:.||::..
Frog    52 QGNRVPRVQEDIAVGVSRSAITYTECLWQK-----TNGTVYVPYTLDDKYSNSEVNTMTSAMEVY 111

  Fly    86 ESISCLTFKEATTDQKYYVNVTSEEGGCFSYIGYLNRVQQLNLQNNEIGVGCFRLYTIVHEFLHA 150
            .:::|:.| ...||:..|||:||.: ||:||:|.....|.::::...    |....|.:||..||
Frog   112 ATLTCVQF-VPYTDEDDYVNITSGD-GCWSYMGRQRGAQVVSVEKGY----CTSEGTTMHELNHA 170

  Fly   151 LGFFHQQSAADRDDYVQIVEENITEGMEFNFDKYTEETVNDFGEKYDYGSVMHYGPYAFSK-NGE 214
            |||.|:||.:|||:||.|:.:.|:.|....|.|...   |:.|..|||.|||||..:|||. .|:
Frog   171 LGFVHEQSRSDRDNYVNIMYQYISPGDVAEFKKMES---NNLGTTYDYRSVMHYPAWAFSNTTGQ 232

  Fly   215 RTILALEEGKEDVIGQRLELSETDIRKLNAIYKC 248
            .||:| :.....:||....::..||.|:|.:|:|
Frog   233 NTIVA-KPNPNIIIGAGNTMTSLDIIKINRLYEC 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15253	NP_609758.1	Astacin	55..250	CDD:279708	68/197 (35%)
CG15253	NP_609758.1	ZnMc_astacin_like	59..246	CDD:239807	66/189 (35%)
astl2d.5	XP_031756347.1	ZnMc	83..265	CDD:412141	67/191 (35%)
		CUB	268..377	CDD:395345
		CUB	382..493	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010