DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15253 and astl2f

DIOPT Version :9

Sequence 1:	NP_609758.1	Gene:	CG15253 / 34916	FlyBaseID:	FBgn0028948	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_002934133.3	Gene:	astl2f / 100495416	XenbaseID:	XB-GENE-22069764	Length:	624	Species:	Xenopus tropicalis

Alignment Length:	235	Identity:	76/235 - (32%)
Similarity:	123/235 - (52%)	Gaps:	27/235 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 IETDPELTAGYIEGDMVP--SGSSRN----IWRNETYRWPNRIIYYHINSYIDEEHRNHIVSAIQ 83
            :|.:.:.....::||::.  ..|:.|    :|...|....|  :.|.|.|..|:..:..|..|:.
Frog   172 LEANKDTNVPLVQGDILEKLGRSTTNCTSCLWPRATSGLVN--VPYTIASVFDDSEQELIQGALN 234

  Fly    84 KIESISCLTFKEATTDQKYYVNVTSEEG-GCFSYIGYLNRVQQLNLQNNEIGVGCFRLYTIVHEF 147
            ::.::||:.||..|.:..:   ::.:.| ||:|.:|.....|::::..:    ||.....|.||.
Frog   235 ELMTLSCIRFKARTIETDF---LSFQSGNGCWSSVGKTGGSQEVSVSKS----GCMSHGIIQHET 292

  Fly   148 LHALGFFHQQSAADRDDYVQIVEENITEGMEFNFDKYTEETVNDFGEKYDYGSVMHYGPYAFSKN 212
            ||||||.|:...:|||:||.|:.:.|:||...:|.|...   |:.|.:|||.||||||.:.|:..
Frog   293 LHALGFIHEHCRSDRDNYVDIIYKYISEGDRSSFTKVNS---NNLGLQYDYSSVMHYGRFTFTNT 354

  Fly   213 -GERTILALEEGKEDV---IGQRLELSETDIRKLNAIYKC 248
             |:.||:.    |.|:   ||||..:|..|:.|||.:|.|
Frog   355 PGQATIIP----KPDLSVPIGQRYGVSSLDVAKLNKLYNC 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15253	NP_609758.1	Astacin	55..250	CDD:279708	69/199 (35%)
CG15253	NP_609758.1	ZnMc_astacin_like	59..246	CDD:239807	67/191 (35%)
astl2f	XP_002934133.3	ZnMc	209..390	CDD:412141	68/196 (35%)
		CUB	394..504	CDD:238001
		CUB	507..621	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100