DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15253 and mep1ba

DIOPT Version :9

Sequence 1:	NP_609758.1	Gene:	CG15253 / 34916	FlyBaseID:	FBgn0028948	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001070089.2	Gene:	mep1ba / 100151009	ZFINID:	ZDB-GENE-041014-209	Length:	677	Species:	Danio rerio

Alignment Length:	267	Identity:	98/267 - (36%)
Similarity:	136/267 - (50%)	Gaps:	29/267 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 CYYSILLLLLVVVNVAWAAPSIRIETDPELTAGY-----------------IEGD-MVPSGSSRN 48
            |.|   |.|.|.|.|. ..|:..:..|.|:...:                 :||| ::..|.|||
Zfish     5 CSY---LFLSVCVTVL-CLPTSSVTGDTEIDVDHGTDLDIFEINEVAGLDLVEGDILIEEGESRN 65

  Fly    49 IWRNETYRWPNRIIYYHINSYIDEEHRNHIVSAIQKIESISCLTFKEATTDQKYYVNVTSEEGGC 113
            ....|.||||..:.|:..|| ::...:..|:.|.::....:|:.||....:..|.  ...:..||
Zfish    66 TILGEQYRWPTTVPYFLDNS-LEINAKGVILKAFEQYRLKTCIDFKPWNGESNYI--FVFKGSGC 127

  Fly   114 FSYIGYLNRVQQLNLQNNEIGVGCFRLYTIVHEFLHALGFFHQQSAADRDDYVQIVEENITEGME 178
            :|.:|  ||  |:..|...||..|..|.|:.||||||||.:|:||.:||||||.||.:.|.:|.|
Zfish   128 YSKVG--NR--QMGKQELSIGSNCDSLGTVEHEFLHALGLWHEQSRSDRDDYVIIVWDQIQDGKE 188

  Fly   179 FNFDKYTEETVNDFGEKYDYGSVMHYGPYAFSKNGERTILALEEGKEDVIGQRLELSETDIRKLN 243
            .||:.|.|...:..|..|||.|||||...:|:|..|.||:.......:|||||:|.|:.|:.|||
Zfish   189 HNFNLYDETQSSSLGVPYDYSSVMHYSKTSFNKGSEPTIVTKIPEFLNVIGQRMEFSDNDLLKLN 253

  Fly   244 AIYKCPT 250
            .:|.|.|
Zfish   254 RLYNCTT 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15253	NP_609758.1	Astacin	55..250	CDD:279708	79/194 (41%)
CG15253	NP_609758.1	ZnMc_astacin_like	59..246	CDD:239807	73/186 (39%)
mep1ba	NP_001070089.2	ZnMc_meprin	29..258	CDD:239809	87/235 (37%)
		Astacin	72..260	CDD:279708	79/194 (41%)
		MAM	268..432	CDD:279023
		MAM	268..430	CDD:99706
		MATH_Meprin_Beta	430..599	CDD:239751
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910