DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15253 and mep1b

DIOPT Version :9

Sequence 1:	NP_609758.1	Gene:	CG15253 / 34916	FlyBaseID:	FBgn0028948	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001096352.1	Gene:	mep1b / 100124942	XenbaseID:	XB-GENE-1001365	Length:	722	Species:	Xenopus tropicalis

Alignment Length:	214	Identity:	86/214 - (40%)
Similarity:	126/214 - (58%)	Gaps:	10/214 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 EGDMVPSGSS-RNIWRNETYRWPNRIIYYHINSYIDEEHRNHIVSAIQKIESISCLTFKEATTDQ 100
            |||::.:.:: ||....:.||||..:.|: :...::...:..::.|.::....:|:.|| ....:
Frog    50 EGDIILADTNQRNSIIGDRYRWPIPVPYF-LEDSLEINAKALVLEAFERYRLKTCIDFK-PWEGE 112

  Fly   101 KYYVNVTSEEGGCFSYIGYLNR-VQQLNLQNNEIGVGCFRLYTIVHEFLHALGFFHQQSAADRDD 164
            ..|::| .::.||:||:|.|.: .|||:|     ||.|.|:.||.|||||||||:|:||.|||||
Frog   113 PNYISV-FKDSGCYSYVGNLRQGKQQLSL-----GVNCDRIATIQHEFLHALGFWHEQSRADRDD 171

  Fly   165 YVQIVEENITEGMEFNFDKYTEETVNDFGEKYDYGSVMHYGPYAFSKNGERTILALEEGKEDVIG 229
            ||.||.:.|..|.|.||:.|.:...|.....|||.|||||...||....|.||:...:...||||
Frog   172 YVTIVWDRILPGREHNFNVYDDTRSNSLNVPYDYTSVMHYSKTAFQNGSEPTIVTKIDAFSDVIG 236

  Fly   230 QRLELSETDIRKLNAIYKC 248
            ||::.|:.|:.|||.:|.|
Frog   237 QRMDFSDYDLEKLNRLYNC 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15253	NP_609758.1	Astacin	55..250	CDD:279708	81/195 (42%)
CG15253	NP_609758.1	ZnMc_astacin_like	59..246	CDD:239807	75/187 (40%)
mep1b	NP_001096352.1	ZnMc	26..255	CDD:412141	85/212 (40%)
		MAM	265..428	CDD:395504
		MATH	427..590	CDD:351761
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	145	1.000	Domainoid score	I4540
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010