Protein Alignment CG15254 and TLL2

DIOPT Version :10

• Sequence 1: NP_609757.1
• Gene: CG15254 / 34915
• FlyBaseID: FBgn0028949
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_036597.1
• Gene: TLL2 / 7093
• HGNCID: 11844
• Length: 1015
• Species: Homo sapiens
• Alignment Length: 211
• Identity: 71/211 - (33%)
• Similarity: 109/211 - (51%)
• Gaps: 9/211 - (4%)

  Fly    45 SPEGRNGLRNETFR-WPNRIVYYYINRDIDTEHRNHILRGIRIIEQSSCLVFKEATTDQEYYVNV 108
            ||..|....:.|.| ||..::.|.|..:.....|....:.:|..|:.:|:.|.| .||:|.::..
Human   144 SPRVRRATTSRTERIWPGGVIPYVIGGNFTGSQRAIFKQAMRHWEKHTCVTFIE-RTDEESFIVF 207

  Fly   109 TSEAGGCYSYVGYRNRVQQLNLQTYALDTGCFRLGTIVHEFLHALGFYHQQSTWNRDDYVRIAEE 173
            :....||.||||.|..    ..|..::...|.:.|.:.||..|.:||:|:.:..:||.:|.|..|
Human   208 SYRTCGCCSYVGRRGG----GPQAISIGKNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRE 268

  Fly   174 NITEGTEGNFNKYDNETVEDYGEPYDYSSVLHYTAYAFSKNGEM-TIVPLQE--GAEELMGQRLQ 235
            ||..|.|.||.|.:...|...||.||:.|::||....||:...: ||:|.|:  |....:|||::
Human   269 NIQPGQEYNFLKMEAGEVSSLGETYDFDSIMHYARNTFSRGVFLDTILPRQDDNGVRPTIGQRVR 333

  Fly   236 MTQSDINKLNVMYKCP 251
            ::|.||.:...:||||
Human   334 LSQGDIAQARKLYKCP 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15254	NP_609757.1	ZnMc_astacin_like	61..248	CDD:239807	60/189 (32%)
TLL2	NP_036597.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..49
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	88..130
		ZnMc_BMP1_TLD	150..349	CDD:239808	66/203 (33%)
		CUB	351..460	CDD:395345
		CUB	464..573	CDD:395345
		FXa_inhibition	580..616	CDD:464251
		CUB	620..729	CDD:395345
		FXa_inhibition	736..771	CDD:464251
		CUB	776..885	CDD:395345
		CUB	889..1002	CDD:395345