DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15254 and bmp1a

DIOPT Version :9

Sequence 1:	NP_001285959.1	Gene:	CG15254 / 34915	FlyBaseID:	FBgn0028949	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001035126.1	Gene:	bmp1a / 572452	ZFINID:	ZDB-GENE-060818-1	Length:	986	Species:	Danio rerio

Alignment Length:	197	Identity:	67/197 - (34%)
Similarity:	106/197 - (53%)	Gaps:	8/197 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 WPNRIVYYYINRDIDTEHRNHILRGIRIIEQSSCLVFKEATTDQEYYVNVTSEAGGCYSYVGYRN 123
            ||..::.|.|:.:.....|....:.:|..|:.:|:.|.|.||::.|.| .|....||.||||.|.
Zfish   119 WPEGVIPYVISGNFSGSQRAIFRQAMRHWEKHTCVTFIERTTEESYIV-FTYRPCGCCSYVGRRG 182

  Fly   124 RVQQLNLQTYALDTGCFRLGTIVHEFLHALGFYHQQSTWNRDDYVRIAEENITEGTEGNFNKYDN 188
            .    ..|..::...|.:.|.:|||..|.:||:|:.:..:||::|.|..:||..|.|.||.|.:.
Zfish   183 G----GPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDEHVSIIRDNIQPGQEYNFLKMEP 243

  Fly   189 ETVEDYGEPYDYSSVLHYTAYAFSKNGEM-TIVPLQE--GAEELMGQRLQMTQSDINKLNVMYKC 250
            ..|:..||.||:.|::||....||:...: ||:|..:  |....:|||.::::.||.:...:|||
Zfish   244 GEVDSLGEVYDFDSIMHYARNTFSRGIFLDTILPRYDVNGVRPPIGQRTRLSKGDIAQARKLYKC 308

  Fly   251 PR 252
            ||
Zfish   309 PR 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15254	NP_001285959.1	Astacin	58..251	CDD:279708	64/194 (33%)
CG15254	NP_001285959.1	ZnMc_astacin_like	61..248	CDD:239807	60/189 (32%)
bmp1a	NP_001035126.1	ZnMc_BMP1_TLD	112..309	CDD:239808	64/194 (33%)
		Astacin	117..309	CDD:279708	64/194 (33%)
		CUB	311..420	CDD:278839	67/197 (34%)
		CUB	424..533	CDD:278839
		FXa_inhibition	544..576	CDD:291342
		CUB	580..699	CDD:278839
		FXa_inhibition	706..741	CDD:291342
		CUB	746..855	CDD:278839
		CUB	859..972	CDD:278839
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810