DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15254 and tld

DIOPT Version :9

Sequence 1:	NP_001285959.1	Gene:	CG15254 / 34915	FlyBaseID:	FBgn0028949	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_524487.2	Gene:	tld / 42945	FlyBaseID:	FBgn0003719	Length:	1067	Species:	Drosophila melanogaster

Alignment Length:	196	Identity:	58/196 - (29%)
Similarity:	100/196 - (51%)	Gaps:	8/196 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 WPNRIVYYYINRDIDTEHRNHILRGIRIIEQSSCLVFKEATTD-QEYYVNVTSEAGGCYSYVGYR 122
            |...::.|.|:......|:....:.:|..|..:|:.|.|...: ...|:..|.:..||.|::|..
  Fly   146 WDYGVIPYEIDTIFSGAHKALFKQAMRHWENFTCIKFVERDPNLHANYIYFTVKNCGCCSFLGKN 210

  Fly   123 NRVQQLNLQTYALDTGCFRLGTIVHEFLHALGFYHQQSTWNRDDYVRIAEENITEGTEGNFNKYD 187
            ..    ..|..::...|.:.|.|:||..|.:||:|:.:..:||.::.|.:.||..|.|.||:...
  Fly   211 GN----GRQPISIGRNCEKFGIIIHELGHTIGFHHEHARGDRDKHIVINKGNIMRGQEYNFDVLS 271

  Fly   188 NETVEDYGEPYDYSSVLHYTAYAFSKNGEM-TIVP--LQEGAEELMGQRLQMTQSDINKLNVMYK 249
            .|.|:....|||.:|::||...:|||:..: ||.|  :..|....:|||.::::.||.:.|::||
  Fly   272 PEEVDLPLLPYDLNSIMHYAKNSFSKSPYLDTITPIGIPPGTHLELGQRKRLSRGDIVQANLLYK 336

  Fly   250 C 250
            |
  Fly   337 C 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15254	NP_001285959.1	Astacin	58..251	CDD:279708	58/196 (30%)
CG15254	NP_001285959.1	ZnMc_astacin_like	61..248	CDD:239807	54/190 (28%)
tld	NP_524487.2	ZnMc_BMP1_TLD	137..338	CDD:239808	58/196 (30%)
		Astacin	144..339	CDD:279708	58/196 (30%)
		CUB	388..474	CDD:214483
		CUB	478..586	CDD:278839
		FXa_inhibition	595..630	CDD:291342
		CUB	634..750	CDD:278839
		FXa_inhibition	757..792	CDD:291342
		CUB	797..906	CDD:278839
		CUB	910..1023	CDD:278839
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444933
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840