DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15254 and tok

DIOPT Version :9

Sequence 1:	NP_001285959.1	Gene:	CG15254 / 34915	FlyBaseID:	FBgn0028949	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001287510.1	Gene:	tok / 42944	FlyBaseID:	FBgn0004885	Length:	1464	Species:	Drosophila melanogaster

Alignment Length:	200	Identity:	65/200 - (32%)
Similarity:	106/200 - (53%)	Gaps:	12/200 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 WPNRIVYYYINRDIDTEHRNHILRGIRIIEQSSCLVFKEATTDQEY---YVNVTSEAGGCYSYVG 120
            |...::.|.|:.:....|:......:|..|.|:|:.|.|  .|.|.   |:..|..:.||.|:||
  Fly   529 WDYGVIPYEIDGNFSGIHKALFKLAMRHWENSTCIKFVE--RDPEIHPNYIVFTVRSCGCCSFVG 591

  Fly   121 YRNRVQQLNLQTYALDTGCFRLGTIVHEFLHALGFYHQQSTWNRDDYVRIAEENITEGTEGNFNK 185
            .|..    ..|..::...|.:.|.:|||..|.:||:|:.:..:|:.:|.|...||.:|.:.|||.
  Fly   592 KRGN----GPQAISIGRNCDKFGIVVHELGHVVGFWHEHTRPDREKHVVIEHNNIMKGQDYNFNM 652

  Fly   186 YDNETVEDYGEPYDYSSVLHYTAYAFSKNGEM-TIVPLQEGAEEL--MGQRLQMTQSDINKLNVM 247
            ...:.|:..|..|||.|::||....|||...: ||:|::....:.  :||||:::|.||.:.|::
  Fly   653 LSPDEVDSLGMAYDYDSIMHYARNTFSKGTYLDTILPIEMKGRKRPEIGQRLRLSQGDIAQANLL 717

  Fly   248 YKCPR 252
            ||||:
  Fly   718 YKCPK 722

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15254	NP_001285959.1	Astacin	58..251	CDD:279708	63/197 (32%)
CG15254	NP_001285959.1	ZnMc_astacin_like	61..248	CDD:239807	60/192 (31%)
tok	NP_001287510.1	ZnMc_BMP1_TLD	520..721	CDD:239808	63/197 (32%)
		Astacin	527..721	CDD:279708	63/197 (32%)
		CUB	723..836	CDD:294042	65/199 (33%)
		CUB	840..951	CDD:278839
		FXa_inhibition	958..993	CDD:291342
		CUB	997..1111	CDD:278839
		FXa_inhibition	1118..1153	CDD:291342
		CUB	1158..1267	CDD:278839
		CUB	1271..1390	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444857
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3510
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.790