DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15254 and nas-39

DIOPT Version :9

Sequence 1:	NP_001285959.1	Gene:	CG15254 / 34915	FlyBaseID:	FBgn0028949	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001360030.1	Gene:	nas-39 / 3565986	WormBaseID:	WBGene00003555	Length:	928	Species:	Caenorhabditis elegans

Alignment Length:	194	Identity:	67/194 - (34%)
Similarity:	104/194 - (53%)	Gaps:	6/194 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 WPNRIVYYYINRDIDTEHRNHILRGIRIIEQSSCLVFKEATTDQEYYVNVTSEAGGCYSYVGYRN 123
            ||..|:.:.|..:...||::..||.:|..|..:|:.|.......::|:..|.:..||.||||.|.
Worm    57 WPEGIIPFVIASNFSGEHQHLFLRAMRHWENFTCVSFVPRQPHHKHYITFTVDKCGCCSYVGRRG 121

  Fly   124 RVQQLNLQTYALDTGCFRLGTIVHEFLHALGFYHQQSTWNRDDYVRIAEENITEGTEGNFNKYDN 188
            .    ..|..::...|.:.|.:|||..|.:||:|:.:..:||.||.|..::|..|.:.||.|...
Worm   122 E----GPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDMYVDIFYKSIQTGQDYNFEKSKP 182

  Fly   189 ETVEDYGEPYDYSSVLHYTAYAFSKNGEM-TIVPLQEGAEEL-MGQRLQMTQSDINKLNVMYKC 250
            |.|:..|||||:||::||....||:.... ||:|.......| :|||:|:::.||.:...:|||
Worm   183 EEVDSLGEPYDFSSIMHYARDTFSRGAFYDTILPKPNSGFRLEIGQRVQLSEGDIRQTKKLYKC 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15254	NP_001285959.1	Astacin	58..251	CDD:279708	67/194 (35%)
CG15254	NP_001285959.1	ZnMc_astacin_like	61..248	CDD:239807	62/188 (33%)
nas-39	NP_001360030.1	ZnMc_BMP1_TLD	48..247	CDD:239808	67/194 (35%)
		CUB	268..343	CDD:214483
		CUB	359..474	CDD:238001
		FXa_inhibition	480..515	CDD:373209
		CUB	519..622	CDD:366096
		FXa_inhibition	629..664	CDD:373209
		CUB	669..780	CDD:238001
		CUB	782..898	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3510
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.760