DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15254 and Mep1a

DIOPT Version :9

Sequence 1:	NP_001285959.1	Gene:	CG15254 / 34915	FlyBaseID:	FBgn0028949	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_037275.1	Gene:	Mep1a / 25684	RGDID:	3080	Length:	748	Species:	Rattus norvegicus

Alignment Length:	269	Identity:	86/269 - (31%)
Similarity:	132/269 - (49%)	Gaps:	29/269 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 WALTLVVIFLASSCSAAPTTQNRIET-----DPEL------------TAG--YIEGDMVPSPEGR 49
            |.|.:.::.|:.|...|..:...:.|     |.::            .||  ..:||:: .|..|
  Rat     3 WTLPVCLLSLSFSAHIAAVSIQHLSTGHDHDDVDVGEQQKDISEINSAAGLNLFQGDIL-LPRTR 66

  Fly    50 NGLRNETFRWPNRIVYYYINRDIDTEHRNHILRGIRIIEQSSCLVFKEATTDQEYYVNVTSEAGG 114
            |.||:.:.||...|.|...: ::|...:..||....:....||:.||....:..|.  :..:..|
  Rat    67 NALRDPSSRWKPPIPYILAD-NLDLNAKGAILNAFEMFRLKSCVDFKPYEGESSYI--IFQQFSG 128

  Fly   115 CYSYVGYRNRVQQLNLQTYALDTGCFRLGTIVHEFLHALGFYHQQSTWNRDDYVRIAEENITEGT 179
            |:|.||.::..|.:     ::..||.....|.||.||||||:|:||..:|||||.|....|....
  Rat   129 CWSMVGDQHVGQNI-----SIGEGCDYKAIIEHEILHALGFFHEQSRTDRDDYVNIWWNEIMTDY 188

  Fly   180 EGNFNKYDNETVEDYGEPYDYSSVLHYTAYAFSKNGEM-TIVPLQEGAEELMGQRLQMTQSDINK 243
            |.|||.||::|:.|...||||.|::||..::|:||..: ||.........::||||..:.:|:.:
  Rat   189 EHNFNTYDDKTITDLNTPYDYESLMHYGPFSFNKNETIPTITTKIPEFNAIIGQRLDFSATDLTR 253

  Fly   244 LNVMYKCPR 252
            ||.||.|.|
  Rat   254 LNRMYNCTR 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15254	NP_001285959.1	Astacin	58..251	CDD:279708	68/193 (35%)
CG15254	NP_001285959.1	ZnMc_astacin_like	61..248	CDD:239807	64/187 (34%)
Mep1a	NP_037275.1	ZnMc	32..260	CDD:294052	78/236 (33%)
		Astacin	75..261	CDD:279708	68/193 (35%)
		MAM	270..433	CDD:279023
		MAM	270..432	CDD:99706
		MATH	432..596	CDD:295307
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	641..668
		EGF	676..710	CDD:278437
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46226
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910