DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG15254 and Tll2

DIOPT Version :9

Sequence 1:NP_001285959.1 Gene:CG15254 / 34915 FlyBaseID:FBgn0028949 Length:254 Species:Drosophila melanogaster
Sequence 2:NP_036034.1 Gene:Tll2 / 24087 MGIID:1346044 Length:1012 Species:Mus musculus


Alignment Length:226 Identity:70/226 - (30%)
Similarity:112/226 - (49%) Gaps:23/226 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 VPSPEGRNGLRNETFR--------------WPNRIVYYYINRDIDTEHRNHILRGIRIIEQSSCL 93
            :|:| |.:....:||.              ||..::.|.|..:.....|....:.:|..|:.:|:
Mouse   127 LPNP-GTSNTTAKTFSARVRRATTSRTERIWPGGVIPYVIGGNFTGTQRAIFKQAMRHWEKHTCV 190

  Fly    94 VFKEATTDQEYYVNVTSEAGGCYSYVGYRNRVQQLNLQTYALDTGCFRLGTIVHEFLHALGFYHQ 158
            .|.| .||:|.::..:....||.||||.|..    ..|..::...|.:.|.:.||..|.:||:|:
Mouse   191 TFVE-RTDEESFIVFSYRTCGCCSYVGRRGG----GPQAISIGKNCDKFGIVAHELGHVVGFWHE 250

  Fly   159 QSTWNRDDYVRIAEENITEGTEGNFNKYDNETVEDYGEPYDYSSVLHYTAYAFSKNGEM-TIVPL 222
            .:..:||.:|.|..|||..|.|.||.|.:...|...||.||:.|::||....||:...: ||:|.
Mouse   251 HTRPDRDQHVTIIRENIQPGQEYNFLKMEAGEVSSLGETYDFDSIMHYARNTFSRGVFLDTILPR 315

  Fly   223 QE--GAEELMGQRLQMTQSDINKLNVMYKCP 251
            ::  |....:|||::::|.||.:...:||||
Mouse   316 RDDNGVRPTIGQRVRLSQGDIAQARKLYKCP 346

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15254NP_001285959.1 Astacin 58..251 CDD:279708 63/209 (30%)
ZnMc_astacin_like 61..248 CDD:239807 59/189 (31%)
Tll2NP_036034.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 83..135 3/8 (38%)
ZnMc_BMP1_TLD 147..346 CDD:239808 63/203 (31%)
Astacin 154..347 CDD:279708 65/198 (33%)
CUB 348..457 CDD:278839
CUB 461..570 CDD:278839
FXa_inhibition 581..613 CDD:291342
CUB 617..726 CDD:278839
FXa_inhibition 733..768 CDD:291342
CUB 773..882 CDD:278839
CUB 886..999 CDD:278839
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3714
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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