DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15254 and Tll1

DIOPT Version :9

Sequence 1:	NP_001285959.1	Gene:	CG15254 / 34915	FlyBaseID:	FBgn0028949	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_033416.2	Gene:	Tll1 / 21892	MGIID:	106923	Length:	1013	Species:	Mus musculus

Alignment Length:	196	Identity:	65/196 - (33%)
Similarity:	104/196 - (53%)	Gaps:	8/196 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 WPNRIVYYYINRDIDTEHRNHILRGIRIIEQSSCLVFKEATTDQEYYVNVTSEAGGCYSYVGYRN 123
            ||..::.|.|..:.....|....:.:|..|:.:|:.|.| .:|:|.|:..|....||.||||.|.
Mouse   157 WPGGVIPYVIGGNFTGSQRAMFKQAMRHWEKHTCVTFTE-RSDEESYIVFTYRPCGCCSYVGRRG 220

  Fly   124 RVQQLNLQTYALDTGCFRLGTIVHEFLHALGFYHQQSTWNRDDYVRIAEENITEGTEGNFNKYDN 188
            .    ..|..::...|.:.|.:|||..|.:||:|:.:..:||::|.|..|||..|.|.||.|.:.
Mouse   221 N----GPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDNHVTIIRENIQPGQEYNFLKMEP 281

  Fly   189 ETVEDYGEPYDYSSVLHYTAYAFSKNGEM-TIVPLQE--GAEELMGQRLQMTQSDINKLNVMYKC 250
            ..|...||.||:.|::||....||:...: ||:|.::  |....:|||.::::.||.:...:|:|
Mouse   282 GEVNSLGERYDFDSIMHYARNTFSRGMFLDTILPSRDDNGIRPAIGQRTRLSKGDIAQARKLYRC 346

  Fly   251 P 251
            |
Mouse   347 P 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15254	NP_001285959.1	Astacin	58..251	CDD:279708	63/194 (32%)
CG15254	NP_001285959.1	ZnMc_astacin_like	61..248	CDD:239807	60/189 (32%)
Tll1	NP_033416.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	124..150
		ZnMc_BMP1_TLD	148..347	CDD:239808	63/194 (32%)
		Astacin	155..348	CDD:279708	65/196 (33%)
		CUB	349..458	CDD:278839
		CUB	462..571	CDD:278839
		FXa_inhibition	582..614	CDD:291342
		CUB	618..727	CDD:278839
		FXa_inhibition	734..769	CDD:291342
		CUB	774..883	CDD:278839
		CUB	887..1000	CDD:278839
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810