DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15254 and nas-27

DIOPT Version :9

Sequence 1:	NP_001285959.1	Gene:	CG15254 / 34915	FlyBaseID:	FBgn0028949	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_493926.2	Gene:	nas-27 / 188809	WormBaseID:	WBGene00003545	Length:	428	Species:	Caenorhabditis elegans

Alignment Length:	261	Identity:	69/261 - (26%)
Similarity:	127/261 - (48%)	Gaps:	23/261 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LTLVVIF---LASSCSAAP----TTQNRIETDPELTAG---YI-EGD--MVPSPEGRNGLRNETF 57
            :.::.||   |.:|..|.|    ..:||.|.|.....|   |: :||  :|.|...|..:|.:..
Worm     1 MQILPIFFPLLITSLHAIPRGRRAVRNRNEGDINSLVGVGQYLYQGDIAVVKSRARRAVIRQKHK 65

  Fly    58 RWPNRIVYYYINRDIDTEHRNHILRGIRIIEQSSCLVFKEATTDQEYYVNVT-SEAGGCYSYVGY 121
            :|...:.|.: :|:..:..|..:|..::...:.:|:.|.|   ::..|.:|: .|..||:|:||
Worm    66 KWKLPMPYSF-DRNFPSRSRQRVLEAMQFWSEKTCVTFHE---NRYVYPHVSIFEGNGCWSFVG- 125

  Fly   122 RNRVQQLNLQTYALDTGCF-RLGTIVHEFLHALGFYHQQSTWNRDDYVRIAEENITEGTEGNFNK 185
              :...|..|:.:|:..|. ....:.||..|.|||||:.:..:||.::.|...|:.......|.|
Worm   126 --KQPSLREQSLSLERSCTDHTFVVAHEIAHTLGFYHEHARGDRDQFISIDYSNVNPNLTFAFAK 188

  Fly   186 YDNETVEDYGEPYDYSSVLHYTAYAFSKNGEMTIVPLQEGA-EELMGQRLQMTQSDINKLNVMYK 249
            ...:.::.....|:|.||:||:...|:.|....::..::.. .:.||.|::.|..|::::||:|.
Worm   189 ESEKQLDHQEAAYEYGSVMHYSVDQFAVNTNRPVIYARDQKFAQAMGNRMRATFQDVSRMNVLYN 253

  Fly   250 C 250
            |
Worm   254 C 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15254	NP_001285959.1	Astacin	58..251	CDD:279708	51/196 (26%)
CG15254	NP_001285959.1	ZnMc_astacin_like	61..248	CDD:239807	48/189 (25%)
nas-27	NP_493926.2	Astacin	65..254	CDD:279708	50/195 (26%)
		ZnMc_astacin_like	70..252	CDD:239807	48/188 (26%)
		CUB	334..410	CDD:294042
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920