DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15254 and nas-29

DIOPT Version :9

Sequence 1:	NP_001285959.1	Gene:	CG15254 / 34915	FlyBaseID:	FBgn0028949	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_494953.3	Gene:	nas-29 / 186488	WormBaseID:	WBGene00003547	Length:	532	Species:	Caenorhabditis elegans

Alignment Length:	204	Identity:	59/204 - (28%)
Similarity:	97/204 - (47%)	Gaps:	18/204 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 WPNRIVYYYINRDIDTEHRNHILRGIRIIEQSSCLVFKEATTDQEYYVNVTSEAGGCYSYVGYRN 123
            |.|.:.:.: :..:....:..||:.:....:.:|:.|...|..:||.:.:.:: .||:|.||
Worm   147 WKNGVAFMF-HESLTPIAKTAILKAVHFWYRETCIEFHPRTFQKEYLLFIGND-DGCWSTVG--- 206

  Fly   124 RVQQLNLQTYALDTGCFRLGTIVHEFLHALGFYHQQSTWNRDDYV----RIAEENITEGTEGNFN 184
            |......|..::..||...|...||..||||.:|:||.::||:.|    |:.|.::.    .||.
Worm   207 RDASQGKQVVSIGNGCEHFGVTSHELAHALGIFHEQSRFDRDESVVFNPRVVERDLL----FNFA 267

  Fly   185 KYDNETVEDYGEPYDYSSVLHYTAYAFSKNGEM-TIVPLQEGAEELMGQRLQMTQSDINKLNVMY 248
            |.....:..||.|||..||:|||...||....: |:..:....::.|||....:..|::.:|..|
Worm   268 KISPRQMSTYGLPYDIGSVMHYTPTEFSNIPSIPTLAAIDTNLQQTMGQLEGPSFVDVHIMNQHY 332

  Fly   249 ----KCPRQ 253
                |||.|
Worm   333 QCQEKCPTQ 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15254	NP_001285959.1	Astacin	58..251	CDD:279708	56/200 (28%)
CG15254	NP_001285959.1	ZnMc_astacin_like	61..248	CDD:239807	53/191 (28%)
nas-29	NP_494953.3	Astacin	145..336	CDD:279708	55/197 (28%)
		ZnMc_astacin_like	148..332	CDD:239807	53/192 (28%)
		CUB	404..491	CDD:214483
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920