DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15254 and nas-1

DIOPT Version :9

Sequence 1:	NP_001285959.1	Gene:	CG15254 / 34915	FlyBaseID:	FBgn0028949	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_499768.2	Gene:	nas-1 / 185811	WormBaseID:	WBGene00003520	Length:	270	Species:	Caenorhabditis elegans

Alignment Length:	239	Identity:	73/239 - (30%)
Similarity:	113/239 - (47%)	Gaps:	26/239 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 PTTQNRIETDPELTAGYIEGDM-VPSPEGRNG----LRNETFRWPNRIVYYYINRDIDTEHRNHI 80
            |||..|       ....:..|| :|....:.|    :..|..:|||..|.|.::....:..|..:
Worm    44 PTTNTR-------RVRSLYHDMRIPFQRFKRGGGVAVAAEKDKWPNGRVPYILSAAYTSAQRAVL 101

  Fly    81 LRGIRIIEQSSCLVF-KEATTDQEYYVNVTSEAGGCY---SYVGYRNRVQQLNLQTYALDTGCFR 141
            .|......:.:|:.| .::..|::|.  |..:..|||   |.||.|.:|        :|...|..
Worm   102 ARAFDTYAKRTCIRFVPKSPADKDYI--VIQKLDGCYADFSRVGGRQQV--------SLADECID 156

  Fly   142 LGTIVHEFLHALGFYHQQSTWNRDDYVRIAEENITEGTEGNFNKYDNETVEDYGEPYDYSSVLHY 206
            ..||:||.:|.:||.|:....:||.||.|..:|:.:|...:|:|..|..:..|||.|||||::||
Worm   157 YATIIHELMHVIGFIHEHQREDRDSYVSILYQNVIQGANTDFDKLSNLGLSYYGEHYDYSSIMHY 221

  Fly   207 TAYAFSKNGEMTIVPLQEGAEELMGQRLQMTQSDINKLNVMYKC 250
            .|...|:||:.||.........:||:....:.||:.::|..|||
Worm   222 EANEGSRNGKNTIEAKNSHFTAIMGKASDFSTSDLRRVNRAYKC 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15254	NP_001285959.1	Astacin	58..251	CDD:279708	64/197 (32%)
CG15254	NP_001285959.1	ZnMc_astacin_like	61..248	CDD:239807	59/190 (31%)
nas-1	NP_499768.2	Astacin	79..266	CDD:279708	64/197 (32%)
nas-1	NP_499768.2	ZnMc_astacin_like	82..263	CDD:239807	59/190 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49330
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.930