DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15254 and nas-28

DIOPT Version :9

Sequence 1:	NP_001285959.1	Gene:	CG15254 / 34915	FlyBaseID:	FBgn0028949	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_498342.3	Gene:	nas-28 / 185658	WormBaseID:	WBGene00003546	Length:	497	Species:	Caenorhabditis elegans

Alignment Length:	209	Identity:	68/209 - (32%)
Similarity:	106/209 - (50%)	Gaps:	11/209 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 RNGLRNETFRWPNRI-VYYYINRDIDTEHRNHILRGIRIIEQSSCLVFKEATTDQEYYVNVTSEA 112
            |..:.:.|..|...: ::|..:..:...:..::.:.|:....:|||.|||....:...  ..|.|
Worm   120 RQAIVDTTNFWSVSVPIFYQFDTKLSATNIANVRKAIQFWNDNSCLSFKEDNNAKNRL--FLSSA 182

  Fly   113 GGCYSYVGYRNRVQQLNL--QTYALDTGCFRLGTIVHEFLHALGFYHQQSTWNRDDYVRIAEENI 175
            |||:||||     :|:::  |..::...|...||..||.:||:||:||||..:||:||.:...||
Worm   183 GGCWSYVG-----KQVDMPYQMVSVGPNCDTFGTATHELMHAIGFWHQQSRADRDNYVYVDFSNI 242

  Fly   176 TEGTEGNFNKYDNETVEDYGEPYDYSSVLHYTAYAFS-KNGEMTIVPLQEGAEELMGQRLQMTQS 239
            ......||.|...:..:....||||.||:.|..|||: .:.:.||:..:.|.:..||||.....|
Worm   243 IPSQAYNFQKMAVDQAQLLNLPYDYGSVMQYYPYAFAVDSSKYTILAKENGFQNSMGQREAPAFS 307

  Fly   240 DINKLNVMYKCPRQ 253
            ||..:|.:|.|..|
Worm   308 DIIGVNKLYNCTSQ 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15254	NP_001285959.1	Astacin	58..251	CDD:279708	64/196 (33%)
CG15254	NP_001285959.1	ZnMc_astacin_like	61..248	CDD:239807	62/190 (33%)
nas-28	NP_498342.3	Astacin	135..320	CDD:279708	64/191 (34%)
		ZnMc_astacin_like	135..316	CDD:239807	62/187 (33%)
		CUB	393..480	CDD:214483
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920