DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15254 and nas-8

DIOPT Version :9

Sequence 1:	NP_001285959.1	Gene:	CG15254 / 34915	FlyBaseID:	FBgn0028949	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_501114.2	Gene:	nas-8 / 183207	WormBaseID:	WBGene00003527	Length:	403	Species:	Caenorhabditis elegans

Alignment Length:	204	Identity:	71/204 - (34%)
Similarity:	107/204 - (52%)	Gaps:	10/204 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 RNGLRNETFRWPNRIVYYYINRDIDTEHRNHILRGIRIIEQSSCLVFKEAT-TDQEY-YVNVTSE 111
            |||:...|.:|||..:.|.|:...:...|..:.|..:.....:|:.|...| .|.:| |:   .:
Worm   111 RNGVITGTRKWPNGRIPYVISNQYNDRERAVLARSFQAYHDKTCVRFVPRTAVDNDYLYI---GK 172

  Fly   112 AGGCYSYVGYRNRVQQLNLQTYALDTGCFRLGTIVHEFLHALGFYHQQSTWNRDDYVRIAEENIT 176
            ..||||.||.....|:|     :||.||.:..|.:||.:|::||||:...|:||:::.|...||.
Worm   173 IDGCYSDVGRAGGRQEL-----SLDNGCLQYDTAIHELMHSVGFYHEHERWDRDEHITILWHNID 232

  Fly   177 EGTEGNFNKYDNETVEDYGEPYDYSSVLHYTAYAFSKNGEMTIVPLQEGAEELMGQRLQMTQSDI 241
            ......|.|.|......||:.|||.|::||.:.||||||..|:|..|.....::|..:..:..||
Worm   233 REAYDQFGKVDLAESSYYGQLYDYYSIMHYDSLAFSKNGFETMVAKQSEMTAVIGAAIDFSPIDI 297

  Fly   242 NKLNVMYKC 250
            .|:|:||:|
Worm   298 LKMNLMYQC 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15254	NP_001285959.1	Astacin	58..251	CDD:279708	67/195 (34%)
CG15254	NP_001285959.1	ZnMc_astacin_like	61..248	CDD:239807	62/188 (33%)
nas-8	NP_501114.2	Astacin	119..308	CDD:279708	67/196 (34%)
		ZnMc_astacin_like	123..304	CDD:239807	62/188 (33%)
		ShK	337..372	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920