DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15254 and nas-4

DIOPT Version :9

Sequence 1:	NP_001285959.1	Gene:	CG15254 / 34915	FlyBaseID:	FBgn0028949	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001254938.1	Gene:	nas-4 / 182259	WormBaseID:	WBGene00003523	Length:	365	Species:	Caenorhabditis elegans

Alignment Length:	238	Identity:	82/238 - (34%)
Similarity:	133/238 - (55%)	Gaps:	21/238 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RIETDPELTAGYIEGD-MVPSPE---------GRNGLRNETFRWPNRIVYYYINRDIDTEHRNHI 80
            :::.||.: ..|.||| ::.||:         |||.::....||||..:.|.::....:..|:.|
Worm    62 KVKDDPTI-GNYSEGDILLESPKKFVEENNKLGRNAIKQIYRRWPNNEIPYTLSSQYGSYARSVI 125

  Fly    81 LRGIRIIEQSSCLVF--KEATTDQEYYVNVTSEAGGCYSYVGYRNRVQQLNLQTYALDTGCFRLG 143
            ...:......:|:.|  ::.:...:|......|  ||||.||...     ..|..:||:||.::|
Worm   126 ANAMNEYHTKTCVKFVARDPSKHHDYLWIHPDE--GCYSLVGKTG-----GKQPVSLDSGCIQVG 183

  Fly   144 TIVHEFLHALGFYHQQSTWNRDDYVRIAEENITEGTEGNFNKYDNETVEDYGEPYDYSSVLHYTA 208
            |||||.:||:||:|:||..:||.|:.:..:|:..|.:..|.||:...:....|||||:|::||..
Worm   184 TIVHELMHAVGFFHEQSRQDRDSYIDVVWQNVMNGADDQFEKYNLNVISHLDEPYDYASIMHYGP 248

  Fly   209 YAFSKNGEMTIVPLQEGAEELMGQRLQMTQSDINKLNVMYKCP 251
            ||||.:|:.|:||.:.|:|. ||||::.:..|:.|:|.:|.||
Worm   249 YAFSGSGKKTLVPKKSGSER-MGQRVKFSDIDVRKINKLYNCP 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15254	NP_001285959.1	Astacin	58..251	CDD:279708	69/194 (36%)
CG15254	NP_001285959.1	ZnMc_astacin_like	61..248	CDD:239807	65/188 (35%)
nas-4	NP_001254938.1	Astacin	102..290	CDD:279708	69/195 (35%)
nas-4	NP_001254938.1	ZnMc_astacin_like	106..287	CDD:239807	65/188 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49330
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.930