DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15254 and nas-6

DIOPT Version :9

Sequence 1:	NP_001285959.1	Gene:	CG15254 / 34915	FlyBaseID:	FBgn0028949	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001040902.1	Gene:	nas-6 / 181796	WormBaseID:	WBGene00003525	Length:	344	Species:	Caenorhabditis elegans

Alignment Length:	273	Identity:	82/273 - (30%)
Similarity:	137/273 - (50%)	Gaps:	41/273 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TWALTLVVIFLASSCSAAPTTQNRIETDPELT------AGYIEGD-------MVPSPEGR---NG 51
            |:.|...|:....|.....:....|..|..:|      :|..:||       ::..|||.   |.
Worm     9 TYCLVSTVVRSQPSADVFRSFAGYIPEDHRVTHHEWQNSGKFQGDIDGVDPNLLKLPEGPVLFNA 73

  Fly    52 LRNETFRWPNRIVYYYINRDIDTEHRNHILRGIRIIE-------QSSCLVF--KEATTDQEYYVN 107
            |:|:...|...::.|    ::||....:   .|:|:|       :::|:.|  :|..||   |:|
Worm    74 LKNKQLTWEGGVIPY----EMDTAFSPN---EIKILEKAFDSYRRTTCIRFEKREGQTD---YLN 128

  Fly   108 VTSEAGGCYSYVGYRNRVQQLNLQTYALDTGCFRLGTIVHEFLHALGFYHQQSTWNRDDYVRIAE 172
            :. :..||||.||.....|::     :|..|||....||||.:|::||:|:.|..:|||:::|..
Worm   129 IV-KGYGCYSQVGRTGGKQEI-----SLGRGCFFHEIIVHELMHSVGFWHEHSRADRDDHIKINW 187

  Fly   173 ENITEGTEGNFNKYDNETVEDYGEPYDYSSVLHYTAYAFSKNGEMTIVPLQEGAEELMGQRLQMT 237
            :||..|.:..|:|......:..||.|||.|::||.:.|||:||..||..::.|..:::|..:.::
Worm   188 DNILPGMKSQFDKISAVLQDLQGENYDYKSIMHYDSTAFSRNGRNTIETVENGFTQVIGTAMDLS 252

  Fly   238 QSDINKLNVMYKC 250
            ..||.|:|.:|.|
Worm   253 PLDIVKINKLYSC 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15254	NP_001285959.1	Astacin	58..251	CDD:279708	66/202 (33%)
CG15254	NP_001285959.1	ZnMc_astacin_like	61..248	CDD:239807	63/195 (32%)
nas-6	NP_001040902.1	Astacin	80..265	CDD:279708	65/200 (33%)
		ZnMc_astacin_like	83..263	CDD:239807	63/195 (32%)
		ShK	299..334	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_112325
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920