DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15254 and hch-1

DIOPT Version :9

Sequence 1:	NP_001285959.1	Gene:	CG15254 / 34915	FlyBaseID:	FBgn0028949	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_510440.1	Gene:	hch-1 / 181564	WormBaseID:	WBGene00001828	Length:	605	Species:	Caenorhabditis elegans

Alignment Length:	261	Identity:	81/261 - (31%)
Similarity:	121/261 - (46%)	Gaps:	46/261 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 QNRIETDPELTAGYIEGDMVPSPE--------------GRNGLRNE---------------TFRW 59
            :::||:.|:......|||||.:.|              .|....||               :.||
Worm    70 EDKIESKPDEIPYLFEGDMVLTDEQMDLIIKNVRDQYWARKSSTNEFLYAIRGKRSMTSFLSERW 134

  Fly    60 PNRIVYYYINRDIDTE---HRNHILRGIRIIEQSSCLVFKE----ATTDQEYYVNVTSEAGGCYS 117
            ...:.||     |||.   :.|.:|.|:...||.:|..|..    :::.::..:...| ..||||
Worm   135 SFPVPYY-----IDTSSGVNTNAVLAGVAKWEQETCARFTRLNSYSSSSRQNALRFIS-GNGCYS 193

  Fly   118 YVGYRNRVQQLNLQTYALDTGCFRLGTIVHEFLHALGFYHQQSTWNRDDYVRIAEENITEGTEGN 182
            .:|..:|..    |..::..||..|||:.||..|||||||:|:.::|||||.|..:||.:.....
Worm   194 NIGKVSRFP----QDVSIGWGCTSLGTVCHEIGHALGFYHEQARYDRDDYVSILTQNIQDMYLSQ 254

  Fly   183 FNKYDNETVEDYGEPYDYSSVLHYTAYAFSKNGEMTIVPLQEGAEELMGQRLQMTQSDINKLNVM 247
            |.|....::.|||..|||.||:||...|||..|..||.......:..:|||:..:.:|:.::|..
Worm   255 FTKQSASSMVDYGVGYDYGSVMHYDQAAFSSTGGNTIATRDPNFQATIGQRVAPSFADVKRINFA 319

  Fly   248 Y 248
            |
Worm   320 Y 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15254	NP_001285959.1	Astacin	58..251	CDD:279708	69/198 (35%)
CG15254	NP_001285959.1	ZnMc_astacin_like	61..248	CDD:239807	66/193 (34%)
hch-1	NP_510440.1	Astacin	132..323	CDD:279708	69/199 (35%)
		ZnMc_astacin_like	135..320	CDD:239807	66/194 (34%)
		CUB	386..466	CDD:214483
		TSP1	533..565	CDD:214559
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910