DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15254 and nas-9

DIOPT Version :9

Sequence 1:	NP_001285959.1	Gene:	CG15254 / 34915	FlyBaseID:	FBgn0028949	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_741532.1	Gene:	nas-9 / 178875	WormBaseID:	WBGene00003528	Length:	546	Species:	Caenorhabditis elegans

Alignment Length:	231	Identity:	67/231 - (29%)
Similarity:	108/231 - (46%)	Gaps:	20/231 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ELTAGYIEGDMVPSPEGRNGL---RNETFRWPN-RIVYYYINRDIDTEHRNHILRGIRIIEQSSC 92
            ::.||...|..||    |:|:   .:...:|.. :.:.|.::..::...:..|...:..|..::|
Worm   287 DVGAGGGGGGRVP----RSGVFFQESAVQKWDIWKPIQYTLDDSLEESDKKDIRDALHEISINTC 347

  Fly    93 LVFKEATTDQEYYVN---VTSEAGGCYSYVGYRNRVQQLNLQTYALDTGCFRLGTIVHEFLHALG 154
            ::|:...|.:.|::|   |.|......||||..:....:.|.....|    ..|..:||.:||||
Worm   348 ILFRYNATPKGYHLNYMKVDSTTFCGLSYVGRTDPANPIYLSFQCGD----NRGVAMHETMHALG 408

  Fly   155 FYHQQSTWNRDDYVRIAEENITEGTEGNFNKYDNETVEDYGEPYDYSSVLHYTAYAFSKN-GEMT 218
            ..||....:||.|::|...||.......|...|.:....||..|.|.|::||.||..:|: .:.|
Worm   409 VSHQHLRLDRDKYIKIDWSNIDPQHYDTFAISDAKLYTSYGTKYAYDSIMHYNAYLGAKDPNKPT 473

  Fly   219 IVPL---QEGAEELMGQRLQMTQSDINKLNVMYKCP 251
            ::||   ||...:| |||.::|:.||..|..||..|
Worm   474 MIPLVNPQENTPKL-GQRAKLTRGDIRLLKKMYCRP 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15254	NP_001285959.1	Astacin	58..251	CDD:279708	59/200 (30%)
CG15254	NP_001285959.1	ZnMc_astacin_like	61..248	CDD:239807	56/194 (29%)
nas-9	NP_741532.1	Astacin	311..505	CDD:279708	57/198 (29%)
		ZnMc_astacin_like	316..505	CDD:239807	56/193 (29%)
		ShKT	510..546	CDD:214586
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010