DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15254 and nas-36

DIOPT Version :9

Sequence 1:	NP_001285959.1	Gene:	CG15254 / 34915	FlyBaseID:	FBgn0028949	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_492109.2	Gene:	nas-36 / 172506	WormBaseID:	WBGene00003552	Length:	617	Species:	Caenorhabditis elegans

Alignment Length:	203	Identity:	61/203 - (30%)
Similarity:	103/203 - (50%)	Gaps:	11/203 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 RNGLRNETFRWPNRIVYYYINRDIDTEHRNHILRGIRIIEQSSCLVFKEA--TTDQEYYVNVTSE 111
            |:.:.::|..|....:.|..:..||....:.|:..||..|.|:|:.|:..  :.|.:|....:.:
Worm   126 RSFVSDKTATWKTMPIKYRFHESIDFYTISQIIAAIRFWEDSTCITFENVSDSPDGDYIEFFSGQ 190

  Fly   112 AGGCYSYVGYRNRVQQLNLQTYALDTGCFRLGTIVHEFLHALGFYHQQSTWNRDDYVRIAEENIT 176
              ||||.:| ||.    ..|..::...|.::|.|.||..||||.:|:||..:...||.|..:.|.
Worm   191 --GCYSMIG-RNG----GRQGISIGESCVKMGVIEHEIGHALGLWHEQSRPDALGYVTIERDFIL 248

  Fly   177 EGTEGNFNKYDNETVEDYGEPYDYSSVLHYTAYAFSKNGE-MTIVPLQEGAEELMGQRLQMTQSD 240
            .....:|.:.|:| ::..|.|||..||:||.:.|||.:.: .|:|......::.:|||.:::..|
Worm   249 PSYISDFLQRDDE-IDTLGIPYDLGSVMHYGSTAFSVDQKSKTVVTRDSLYQQTIGQREKLSFYD 312

  Fly   241 INKLNVMY 248
            :..:|..|
Worm   313 VATINTAY 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15254	NP_001285959.1	Astacin	58..251	CDD:279708	59/194 (30%)
CG15254	NP_001285959.1	ZnMc_astacin_like	61..248	CDD:239807	57/189 (30%)
nas-36	NP_492109.2	Astacin	134..323	CDD:279708	59/195 (30%)
		ZnMc_astacin_like	140..320	CDD:239807	57/187 (30%)
		CUB	380..478	CDD:214483
		TSP1	510..556	CDD:214559
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820