DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15254 and XB5917669

DIOPT Version :9

Sequence 1:	NP_001285959.1	Gene:	CG15254 / 34915	FlyBaseID:	FBgn0028949	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_031756322.1	Gene:	XB5917669 / 100496293	XenbaseID:	XB-GENE-5917670	Length:	578	Species:	Xenopus tropicalis

Alignment Length:	260	Identity:	78/260 - (30%)
Similarity:	118/260 - (45%)	Gaps:	60/260 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ELTAGYIEGDMVPSPEG-----------RNGL-------------------------RNETFRWP 60
            ||...::||...|..:|           .||:                         .|||...|
Frog   106 ELCVSFLEGKSDPFGQGDVFSRILKANQGNGVPRVQEDIAVGVSRSAITSTECLWQKTNETVYVP 170

  Fly    61 NRIVYYYINRDIDTEHRNHILRGIRIIEQSSCLVFKEATTDQEYYVNVTSEAGGCYSYVGYRNRV 125
            ..:...|.|.:::|     :...:.:....:|:.| ...||::.|||:|| ..||:||:|
Frog   171 YTLDSKYSNSEVNT-----MTSAMEVYATLTCVQF-VPYTDEDDYVNITS-GDGCWSYMG----- 223

  Fly   126 QQLNLQTYALDTG-CFRLGTIVHEFLHALGFYHQQSTWNRDDYVRIAEENITEGTEGNF---NKY 186
            :|...|..:::.| |...||.:||..|||||.|:.|..:||:||.|..:.|:.|...||   |..
Frog   224 RQGGAQVVSVEKGYCTSEGTTMHELNHALGFVHEHSRSDRDNYVNIMYQYISPGDIVNFEIMNTN 288

  Fly   187 DNETVEDYGEPYDYSSVLHYTAYAFSK-NGEMTIVPLQEGAEELMGQRLQMTQSDINKLNVMYKC 250
            :..|:      |||.|::||.|:|||. .|:.||| .:.....::|....||..||.|:|.:|:|
Frog   289 NLNTI------YDYRSIMHYPAWAFSNTTGKNTIV-AKLNPNIIIGAGSTMTSLDIIKINRLYEC 346

Fly 251 250
Frog 347 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15254	NP_001285959.1	Astacin	58..251	CDD:279708	67/198 (34%)
CG15254	NP_001285959.1	ZnMc_astacin_like	61..248	CDD:239807	64/191 (34%)
XB5917669	XP_031756322.1	C2	92..>113	CDD:417471	2/6 (33%)
		ZnMc	164..346	CDD:412141	69/200 (35%)
		CUB	349..458	CDD:395345
		CUB	463..574	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010