DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15254 and astl2d.5

DIOPT Version :9

Sequence 1:	NP_001285959.1	Gene:	CG15254 / 34915	FlyBaseID:	FBgn0028949	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_031756347.1	Gene:	astl2d.5 / 100495579	XenbaseID:	XB-GENE-22069752	Length:	497	Species:	Xenopus tropicalis

Alignment Length:	230	Identity:	75/230 - (32%)
Similarity:	115/230 - (50%)	Gaps:	34/230 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 EGDMVPSPE-------GRNGLRNETFRW--PNRIVYY-------YINRDIDTEHRNHILRGIRII 87
            :|:.||..:       .|:.:......|  .|..||.       |.|.:::|     :...:.:.
Frog    52 QGNRVPRVQEDIAVGVSRSAITYTECLWQKTNGTVYVPYTLDDKYSNSEVNT-----MTSAMEVY 111

  Fly    88 EQSSCLVFKEATTDQEYYVNVTSEAGGCYSYVGYRNRVQQLNLQTYALDTG-CFRLGTIVHEFLH 151
            ...:|:.| ...||::.|||:|| ..||:||:|     :|...|..:::.| |...||.:||..|
Frog   112 ATLTCVQF-VPYTDEDDYVNITS-GDGCWSYMG-----RQRGAQVVSVEKGYCTSEGTTMHELNH 169

  Fly   152 ALGFYHQQSTWNRDDYVRIAEENITEGTEGNFNKYDNETVEDYGEPYDYSSVLHYTAYAFSK-NG 215
            ||||.|:||..:||:||.|..:.|:.|....|.|.::..:   |..|||.||:||.|:|||. .|
Frog   170 ALGFVHEQSRSDRDNYVNIMYQYISPGDVAEFKKMESNNL---GTTYDYRSVMHYPAWAFSNTTG 231

  Fly   216 EMTIVPLQEGAEELMGQRLQMTQSDINKLNVMYKC 250
            :.||| .:.....::|....||..||.|:|.:|:|
Frog   232 QNTIV-AKPNPNIIIGAGNTMTSLDIIKINRLYEC 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15254	NP_001285959.1	Astacin	58..251	CDD:279708	71/204 (35%)
CG15254	NP_001285959.1	ZnMc_astacin_like	61..248	CDD:239807	68/195 (35%)
astl2d.5	XP_031756347.1	ZnMc	83..265	CDD:412141	69/197 (35%)
		CUB	268..377	CDD:395345
		CUB	382..493	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010