DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15254 and astl3b.2

DIOPT Version :9

Sequence 1:	NP_001285959.1	Gene:	CG15254 / 34915	FlyBaseID:	FBgn0028949	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_031746779.1	Gene:	astl3b.2 / 100491112	XenbaseID:	XB-GENE-22069683	Length:	529	Species:	Xenopus tropicalis

Alignment Length:	217	Identity:	80/217 - (36%)
Similarity:	119/217 - (54%)	Gaps:	16/217 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 EGDMVPSPEGRNGLRNETFRWPNR-----IVYYYINRDIDTEHRNHILRGIRIIEQSSCLVFKEA 98
            :||:: .|:||:.:......||..     ||.|..:.:...:........::..|..:|:.|...
Frog    97 QGDIL-RPKGRSAMNCTECLWPKSTDGTVIVPYNFSSNYSADQLALFKSTMQEYESLTCVRFVPR 160

  Fly    99 TTDQEYYVNVTSEAGGCYSYVGYRNRVQQLNLQTYALDTGCFRLGTIVHEFLHALGFYHQQSTWN 163
            ..:.: ::::.|: .||.|::|.....|.:.|.:|    ||...|.|.||..|||||||:||..:
Frog   161 ANETD-FLSIVSD-NGCASFLGKVGGDQTVQLDSY----GCIYRGIIQHELNHALGFYHEQSRSD 219

  Fly   164 RDDYVRIAEENITEGTEGNFNKYDNETVEDYGEPYDYSSVLHYTAYAFSKNGEMTIVPLQEGAEE 228
            |||||.|..|||..|.||||||.|:..:   |..||||||:||...||||||.:||||..:....
Frog   220 RDDYVTIHTENIIPGYEGNFNKADSNNL---GLEYDYSSVMHYPGDAFSKNGNLTIVPKPDPTVP 281

  Fly   229 LMGQRLQMTQSDINKLNVMYKC 250
            : |||..::..|::|:|.:|:|
Frog   282 I-GQRDGLSILDVSKINRLYQC 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15254	NP_001285959.1	Astacin	58..251	CDD:279708	75/198 (38%)
CG15254	NP_001285959.1	ZnMc_astacin_like	61..248	CDD:239807	71/191 (37%)
astl3b.2	XP_031746779.1	ZnMc_hatching_enzyme	121..302	CDD:239810	72/190 (38%)
		CUB	306..414	CDD:238001
		CUB	419..527	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010