DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15254 and mep1ba

DIOPT Version :9

Sequence 1:	NP_001285959.1	Gene:	CG15254 / 34915	FlyBaseID:	FBgn0028949	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001070089.2	Gene:	mep1ba / 100151009	ZFINID:	ZDB-GENE-041014-209	Length:	677	Species:	Danio rerio

Alignment Length:	265	Identity:	89/265 - (33%)
Similarity:	134/265 - (50%)	Gaps:	34/265 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LASSCS-----------AAPTTQNRIETDPELTAG---------------YIEGD-MVPSPEGRN 50
            :||:||           ..||:....:|:.::..|               .:||| ::...|.||
Zfish     1 MASACSYLFLSVCVTVLCLPTSSVTGDTEIDVDHGTDLDIFEINEVAGLDLVEGDILIEEGESRN 65

  Fly    51 GLRNETFRWPNRIVYYYINRDIDTEHRNHILRGIRIIEQSSCLVFKEATTDQEYYVNVTSEAGGC 115
            .:..|.:|||. .|.|:::..::...:..||:........:|:.||....:..|.  ...:..||
Zfish    66 TILGEQYRWPT-TVPYFLDNSLEINAKGVILKAFEQYRLKTCIDFKPWNGESNYI--FVFKGSGC 127

  Fly   116 YSYVGYRNRVQQLNLQTYALDTGCFRLGTIVHEFLHALGFYHQQSTWNRDDYVRIAEENITEGTE 180
            ||.||.|    |:..|..::.:.|..|||:.||||||||.:|:||..:|||||.|..:.|.:|.|
Zfish   128 YSKVGNR----QMGKQELSIGSNCDSLGTVEHEFLHALGLWHEQSRSDRDDYVIIVWDQIQDGKE 188

  Fly   181 GNFNKYDNETVEDYGEPYDYSSVLHYTAYAFSKNGEMTIVPLQEGAEELMGQRLQMTQSDINKLN 245
            .|||.||.......|.|||||||:||:..:|:|..|.|||........::|||::.:.:|:.|||
Zfish   189 HNFNLYDETQSSSLGVPYDYSSVMHYSKTSFNKGSEPTIVTKIPEFLNVIGQRMEFSDNDLLKLN 253

  Fly   246 VMYKC 250
            .:|.|
Zfish   254 RLYNC 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15254	NP_001285959.1	Astacin	58..251	CDD:279708	74/193 (38%)
CG15254	NP_001285959.1	ZnMc_astacin_like	61..248	CDD:239807	69/186 (37%)
mep1ba	NP_001070089.2	ZnMc_meprin	29..258	CDD:239809	81/235 (34%)
		Astacin	72..260	CDD:279708	74/194 (38%)
		MAM	268..432	CDD:279023
		MAM	268..430	CDD:99706
		MATH_Meprin_Beta	430..599	CDD:239751
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm25214
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910