DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Semp1 and cuzd1.2

DIOPT Version :9

Sequence 1:	NP_609756.1	Gene:	Semp1 / 34914	FlyBaseID:	FBgn0028944	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_021323075.1	Gene:	cuzd1.2 / 555768	ZFINID:	ZDB-GENE-131119-30	Length:	718	Species:	Danio rerio

Alignment Length:	124	Identity:	26/124 - (20%)
Similarity:	45/124 - (36%)	Gaps:	21/124 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 FRIGSIIHELLHVLGFEHQHVSQNRD-QYVSI---QWKNINPQYNINFVNNDNSTAWHDFDEGYD 197
            |...:..|..::..|::....|..|| .|..|   .:.:..|.|.   ...|::|..| :.|.:.
Zfish   268 FEPDTTAHSCMYNCGYDLGSCSCARDCHYYDICCPDYDSHCPSYT---TLRDSTTELH-YTESHP 328

  Fly   198 YESVMHYVPRAFSRNGQPTIVPLREGA-------ENMGQRFYMSEKDIRKLNKMYRCPD 249
            ......|....||....|:.  ..:.|       ...|||.:::..|:    ::.||.|
Zfish   329 KCGGHLYGAGLFSTPNYPSY--YHDNAYCVWYLSAQQGQRIFLTFADV----QLERCCD 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Semp1	NP_609756.1	Astacin	53..249	CDD:279708	25/122 (20%)
Semp1	NP_609756.1	ZnMc_astacin_like	55..245	CDD:239807	23/118 (19%)
cuzd1.2	XP_021323075.1	CUB	21..127	CDD:238001
		Somatomedin_B	131..164	CDD:307259
		Somatomedin_B	175..214	CDD:321959
		Somatomedin_B	<239..260	CDD:307259
		CUB	330..439	CDD:238001	12/58 (21%)
		ZP	450..694	CDD:214579
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900