Protein Alignment Semp1 and ASTL

DIOPT Version :9

• Sequence 1: NP_609756.1
• Gene: Semp1 / 34914
• FlyBaseID: FBgn0028944
• Length: 251
• Species: Drosophila melanogaster
• Sequence 2: XP_011509507.1
• Gene: ASTL / 431705
• HGNCID: 31704
• Length: 436
• Species: Homo sapiens
• Alignment Length: 232
• Identity: 80/232 - (34%)
• Similarity: 118/232 - (50%)
• Gaps: 41/232 - (17%)

  Fly    32 QGD-IKAHPIRTRNGIVNQIYHWPNR-----TVPYMIEDDAFADSHYRE-----ILRAISIIEEN 85
            :|| |:..|.|..:...|:   ||..     .||:::      .|.|.|     ||.|::..|.:
Human    80 EGDIIRPSPFRLLSATSNK---WPMGGSGVVEVPFLL------SSKYDEPSRQVILEALAEFERS 135

  Fly    86 SCVIFKP-ATEMDF----PMALVITSKGLGCNTVHLGYRNKTQVVNLEIYPLGEGCFRIGSIIHE 145
            :|:.|.. ..:.||    ||        .||.: .:|.....|||:|....|.:|   .|.::||
Human   136 TCIRFVTYQDQRDFISIIPM--------YGCFS-SVGRSGGMQVVSLAPTCLQKG---RGIVLHE 188

  Fly   146 LLHVLGFEHQHVSQNRDQYVSIQWKNINPQYNINFVNNDNSTAWHDFDEGYDYESVMHYVPRAFS 210
            |:|||||.|:|...:||:|:.:.|..|.|.:.|||:.:.:|    :....|||.|||||...|||
Human   189 LMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSQSS----NMLTPYDYSSVMHYGRLAFS 249

  Fly   211 RNGQPTIVPLREGAENMGQRFYMSEKDIRKLNKMYRC 247
            |.|.|||.||...:.::|||:.:|..||.::.|:|.|
Human   250 RRGLPTITPLWAPSVHIGQRWNLSASDITRVLKLYGC 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Semp1	NP_609756.1	Astacin	53..249	CDD:279708	74/210 (35%)
		ZnMc_astacin_like	55..245	CDD:239807	70/204 (34%)
ASTL	XP_011509507.1	Astacin	97..288	CDD:279708	75/215 (35%)
		ZnMc	105..286	CDD:294052	71/202 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5777
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.870