DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Semp1 and CG6763

DIOPT Version :9

Sequence 1:	NP_609756.1	Gene:	Semp1 / 34914	FlyBaseID:	FBgn0028944	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_001262871.1	Gene:	CG6763 / 42754	FlyBaseID:	FBgn0039069	Length:	354	Species:	Drosophila melanogaster

Alignment Length:	230	Identity:	86/230 - (37%)
Similarity:	119/230 - (51%)	Gaps:	17/230 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 DPELLAGFYQGD--IKAHPIRTRNGIVNQIYHWPNRTVPYMIEDDAFADSHYREILRAISIIEEN 85
            :||.|..:.:||  :....:..:||:..|...|||..|||.|..: |.......|..||......
  Fly    85 NPEELGSYLEGDMLVPQTDLIMKNGLPTQSSRWPNGVVPYEIRGN-FNARDMATIENAIGEYHRR 148

  Fly    86 SCVIF-KPATEMDFPMALVITSKGLGCNTVHLGYRNKTQVVNLEIYPLGEGCF-RIGSIIHELLH 148
            :|:.| |.::|.|:   :.|.....||.: .:|.....|.|||:    ..||. |.|:.:|||:|
  Fly   149 TCIRFVKRSSERDY---ISIRGDNSGCWS-SVGRVGGKQEVNLQ----SPGCLSRPGTAMHELMH 205

  Fly   149 VLGFEHQHVSQNRDQYVSIQWKNINPQYNINFVNNDNSTAWHDFDEGYDYESVMHYVPRAFSRNG 213
            .|||.|:.....||.||:||:.|:......||   :.:.....|...|||.|||||...|||.||
  Fly   206 ALGFLHEQNRMERDGYVAIQYNNVQSSAMNNF---EKAARTEAFGVPYDYGSVMHYSKNAFSING 267

  Fly   214 QPTIVPLR-EGAENMGQRFYMSEKDIRKLNKMYRC 247
            ||||:.:: .||:.||||...|:.||:|||:||.|
  Fly   268 QPTILAMQANGADKMGQRNGFSDYDIQKLNRMYDC 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Semp1	NP_609756.1	Astacin	53..249	CDD:279708	78/198 (39%)
Semp1	NP_609756.1	ZnMc_astacin_like	55..245	CDD:239807	73/192 (38%)
CG6763	NP_001262871.1	Astacin	116..304	CDD:279708	78/199 (39%)
CG6763	NP_001262871.1	ZnMc_astacin_like	119..300	CDD:239807	73/192 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444833
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5777
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D115954at6960
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.800