DRSC/TRiP Functional Genomics Resources

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Protein Alignment Semp1 and Tll2

DIOPT Version :9

Sequence 1:NP_609756.1 Gene:Semp1 / 34914 FlyBaseID:FBgn0028944 Length:251 Species:Drosophila melanogaster
Sequence 2:NP_001178827.1 Gene:Tll2 / 365460 RGDID:1559756 Length:1014 Species:Rattus norvegicus


Alignment Length:201 Identity:65/201 - (32%)
Similarity:105/201 - (52%) Gaps:15/201 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    53 WPNRTVPYMIEDDAFADSHYREILRAISIIEENSCVIFKPATEMDFPMALVITSKGLGCNTVHLG 117
            ||...:||:|..: |..:......:|:...|:::||.|...|  |....:|.:.:..||.: ::|
  Rat   158 WPGGVIPYVIGGN-FTGTQRAIFKQAMRHWEKHTCVTFIERT--DEESFIVFSYRTCGCCS-YVG 218

  Fly   118 YR-NKTQVVNLEIYPLGEGCFRIGSIIHELLHVLGFEHQHVSQNRDQYVSIQWKNINPQYNINFV 181
            .| ...|.::     :|:.|.:.|.:.|||.||:||.|:|...:|||:|:|..:||.|....||:
  Rat   219 RRGGGPQAIS-----IGKNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQPGQEYNFL 278

  Fly   182 NNDNSTAWHDFDEGYDYESVMHYVPRAFSRN-GQPTIVPLREG---AENMGQRFYMSEKDIRKLN 242
            ..:.... ....|.||::|:|||....|||. ...||:|.|:.   ...:|||..:|:.||.:..
  Rat   279 KMEAGEV-SSLGETYDFDSIMHYARNTFSRGVFLDTILPRRDDNGVRPTIGQRVRLSQGDIAQAR 342

  Fly   243 KMYRCP 248
            |:|:||
  Rat   343 KLYKCP 348

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Semp1NP_609756.1 Astacin 53..249 CDD:279708 65/201 (32%)
ZnMc_astacin_like 55..245 CDD:239807 60/194 (31%)
Tll2NP_001178827.1 ZnMc_BMP1_TLD 149..348 CDD:239808 63/199 (32%)
Astacin 156..349 CDD:279708 65/201 (32%)
CUB 350..459 CDD:278839
CUB 463..572 CDD:278839
FXa_inhibition 583..615 CDD:291342
CUB 619..728 CDD:278839
FXa_inhibition 735..770 CDD:291342
CUB 775..884 CDD:278839
CUB 888..1001 CDD:278839
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3714
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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