DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Semp1 and CG15254

DIOPT Version :9

Sequence 1:	NP_609756.1	Gene:	Semp1 / 34914	FlyBaseID:	FBgn0028944	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_001285959.1	Gene:	CG15254 / 34915	FlyBaseID:	FBgn0028949	Length:	254	Species:	Drosophila melanogaster

Alignment Length:	250	Identity:	121/250 - (48%)
Similarity:	157/250 - (62%)	Gaps:	11/250 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VIFLFT-----PTVFSELFKDPELLAGFYQGDIKAHPIRTRNGIVNQIYHWPNRTVPYMIEDDAF 67
            ||||.:     ||..:.:..||||.||:.:||:...| ..|||:.|:.:.||||.|.|.|..|..
  Fly    10 VIFLASSCSAAPTTQNRIETDPELTAGYIEGDMVPSP-EGRNGLRNETFRWPNRIVYYYINRDID 73

  Fly    68 ADSHYREILRAISIIEENSCVIFKPATEMDFPMALVITSKGLGCNTVHLGYRNKTQVVNLEIYPL 132
            .: |...|||.|.|||::||::||.|| .|....:.:||:..||.: ::||||:.|.:||:.|.|
  Fly    74 TE-HRNHILRGIRIIEQSSCLVFKEAT-TDQEYYVNVTSEAGGCYS-YVGYRNRVQQLNLQTYAL 135

  Fly   133 GEGCFRIGSIIHELLHVLGFEHQHVSQNRDQYVSIQWKNINPQYNINFVNNDNSTAWHDFDEGYD 197
            ..||||:|:|:||.||.|||.||..:.|||.||.|..:||......||...||.|. .|:.|.||
  Fly   136 DTGCFRLGTIVHEFLHALGFYHQQSTWNRDDYVRIAEENITEGTEGNFNKYDNETV-EDYGEPYD 199

  Fly   198 YESVMHYVPRAFSRNGQPTIVPLREGAEN-MGQRFYMSEKDIRKLNKMYRCPDHV 251
            |.||:||...|||:||:.|||||:||||. ||||..|::.||.|||.||:||..|
  Fly   200 YSSVLHYTAYAFSKNGEMTIVPLQEGAEELMGQRLQMTQSDINKLNVMYKCPRQV 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Semp1	NP_609756.1	Astacin	53..249	CDD:279708	100/196 (51%)
Semp1	NP_609756.1	ZnMc_astacin_like	55..245	CDD:239807	95/190 (50%)
CG15254	NP_001285959.1	Astacin	58..251	CDD:279708	99/196 (51%)
CG15254	NP_001285959.1	ZnMc_astacin_like	61..248	CDD:239807	95/190 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444829
Domainoid	1	1.000	145	1.000	Domainoid score	I4540
eggNOG	1	0.900	-	-		E1_KOG3714
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49330
OrthoDB	1	1.010	-	-		D109979at50557
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.860