DRSC/TRiP Functional Genomics Resources

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Protein Alignment Semp1 and Tnfaip6

DIOPT Version :9

Sequence 1:NP_609756.1 Gene:Semp1 / 34914 FlyBaseID:FBgn0028944 Length:251 Species:Drosophila melanogaster
Sequence 2:NP_033424.1 Gene:Tnfaip6 / 21930 MGIID:1195266 Length:275 Species:Mus musculus


Alignment Length:206 Identity:40/206 - (19%)
Similarity:78/206 - (37%) Gaps:45/206 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    36 KAHPIRTRNGIVNQ---------IYHWPNRTVPYMIEDDAFADSHYREILRAISIIEENSCVIFK 91
            :||....:|||.:.         :||...|...|.:   .:|::      :|:...|......:|
Mouse    14 EAHGWGFKNGIFHNSIWLEQAAGVYHREARAGRYKL---TYAEA------KAVCEFEGGRLATYK 69

  Fly    92 ---PATEMDFPMALV-----------ITSKGLGC-----NTVHLGYR-NKTQVVNLEIY-PLGEG 135
               .|.::.|.:...           |...|..|     ..:..|.| |:::..:...| |..:.
Mouse    70 QLEAARKIGFHVCAAGWMAKGRVGYPIVKPGPNCGFGKTGIIDYGIRLNRSERWDAYCYNPHAKE 134

  Fly   136 CFRIGSIIHELLHVLGFEHQHVSQNRDQYVSIQWKNINPQYNINFVNND---NSTAWHDFDEGYD 197
            |..:.:....:....||.::: ..|:..|..|:.| ...:.:::|::.|   :.....|:.|.||
Mouse   135 CGGVFTDPKRIFKSPGFPNEY-DDNQVCYWHIRLK-YGQRIHLSFLDFDLEHDPGCLADYVEIYD 197

  Fly   198 -YESVMHYVPR 207
             |:.|..:|.|
Mouse   198 SYDDVHGFVGR 208

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Semp1NP_609756.1 Astacin 53..249 CDD:279708 33/180 (18%)
ZnMc_astacin_like 55..245 CDD:239807 33/178 (19%)
Tnfaip6NP_033424.1 Link_domain_TSG_6_like 36..128 CDD:239592 16/100 (16%)
CUB 135..244 CDD:278839 17/76 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 253..275
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3714
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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