DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Semp1 and nas-31

DIOPT Version :9

Sequence 1:	NP_609756.1	Gene:	Semp1 / 34914	FlyBaseID:	FBgn0028944	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_001023994.1	Gene:	nas-31 / 186493	WormBaseID:	WBGene00003549	Length:	611	Species:	Caenorhabditis elegans

Alignment Length:	207	Identity:	60/207 - (28%)
Similarity:	102/207 - (49%)	Gaps:	29/207 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 NQIYHWPNRT-VPYMIEDDAFADSHYREILRAISIIEENSCV-IFKPATEMDFPMALVITSKGLG 110
            :.:|::.:|| .|.:::  ||.        :|::..:..:|: |.:.:|.::    .:...||.|
Worm   173 SSVYYYYDRTATPKIVK--AFE--------QAVAFWQNVTCINIMQSSTAIN----RIRVFKGQG 223

  Fly   111 CNTVHLGYRNKTQVVNLEIYPLGEGCFRIGSIIHELLHVLGFEHQHVSQNRDQYVSIQWKNINPQ 175
            |      |....::..::...||.||...|:..|||.|.|||.|.....:||.|:||.:.||:|.
Worm   224 C------YSYVGRISGVQDLSLGTGCEEFGTAAHELGHALGFFHTQSRYDRDNYISINYANIDPS 282

  Fly   176 YNINFVNNDNSTAWHDFDEG--YDYESVMHYVPRAFSRNGQPTIVPL-REGAENMGQRFYMSEKD 237
            |...|   |..|:..:|:.|  |||.|:|.|...:.|.|.:.|::.. .|..:.||..| :...|
Worm   283 YVEQF---DKETSNTNFNYGMPYDYGSIMQYGATSASSNDKATMIARDTEYQDTMGSDF-VGFYD 343

  Fly   238 IRKLNKMYRCPD 249
            |..:|:.|:|.:
Worm   344 ISMMNEHYKCKE 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Semp1	NP_609756.1	Astacin	53..249	CDD:279708	59/200 (30%)
Semp1	NP_609756.1	ZnMc_astacin_like	55..245	CDD:239807	57/194 (29%)
nas-31	NP_001023994.1	Astacin	169..355	CDD:279708	60/205 (29%)
		ZnMc_astacin_like	175..351	CDD:239807	58/199 (29%)
		ShKT	532..564	CDD:214586
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010