DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Semp1 and nas-9

DIOPT Version :9

Sequence 1:	NP_609756.1	Gene:	Semp1 / 34914	FlyBaseID:	FBgn0028944	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_741532.1	Gene:	nas-9 / 178875	WormBaseID:	WBGene00003528	Length:	546	Species:	Caenorhabditis elegans

Alignment Length:	215	Identity:	62/215 - (28%)
Similarity:	110/215 - (51%)	Gaps:	15/215 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 RNGIVNQ---IYHWPN-RTVPYMIEDDAFADSHYREILRAISIIEENSCVIFK-PATEMDFPMAL 102
            |:|:..|   :..|.. :.:.|.: ||:..:|..::|..|:..|..|:|::|: .||...:.:..
Worm   300 RSGVFFQESAVQKWDIWKPIQYTL-DDSLEESDKKDIRDALHEISINTCILFRYNATPKGYHLNY 363

  Fly   103 VITSKGLGCNTVHLGYRNKTQVVNLEIYPLGEGCFRIGSIIHELLHVLGFEHQHVSQNRDQYVSI 167
            :.......|...::|..:....:.|. :..|:   ..|..:||.:|.||..|||:..:||:|:.|
Worm   364 MKVDSTTFCGLSYVGRTDPANPIYLS-FQCGD---NRGVAMHETMHALGVSHQHLRLDRDKYIKI 424

  Fly   168 QWKNINPQYNINFVNNDNSTAWHDFDEGYDYESVMHYVPRAFSRN-GQPTIVPL---REGAENMG 228
            .|.||:||:...|..:| :..:..:...|.|:|:|||.....::: .:||::||   :|....:|
Worm   425 DWSNIDPQHYDTFAISD-AKLYTSYGTKYAYDSIMHYNAYLGAKDPNKPTMIPLVNPQENTPKLG 488

  Fly   229 QRFYMSEKDIRKLNKMYRCP 248
            ||..::..|||.|.|||..|
Worm   489 QRAKLTRGDIRLLKKMYCRP 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Semp1	NP_609756.1	Astacin	53..249	CDD:279708	59/202 (29%)
Semp1	NP_609756.1	ZnMc_astacin_like	55..245	CDD:239807	55/195 (28%)
nas-9	NP_741532.1	Astacin	311..505	CDD:279708	56/199 (28%)
		ZnMc_astacin_like	316..505	CDD:239807	55/194 (28%)
		ShKT	510..546	CDD:214586
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010