DRSC/TRiP Functional Genomics Resources

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Protein Alignment Semp1 and Bmp1

DIOPT Version :10

Sequence 1:NP_609756.1 Gene:Semp1 / 34914 FlyBaseID:FBgn0028944 Length:251 Species:Drosophila melanogaster
Sequence 2:NP_033885.2 Gene:Bmp1 / 12153 MGIID:88176 Length:991 Species:Mus musculus


Alignment Length:201 Identity:68/201 - (33%)
Similarity:110/201 - (54%) Gaps:15/201 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    53 WPNRTVPYMIEDDAFADSHYREILRAISIIEENSCVIFKPATEMDFPMALVITSKGLGCNTVHLG 117
            ||:..:|::|..: |..|......:|:...|:::||.|...|:.|  ..:|.|.:..||.: ::|
Mouse   135 WPDGVIPFVIGGN-FTGSQRAVFRQAMRHWEKHTCVTFLERTDED--SYIVFTYRPCGCCS-YVG 195

  Fly   118 YR-NKTQVVNLEIYPLGEGCFRIGSIIHELLHVLGFEHQHVSQNRDQYVSIQWKNINPQYNINFV 181
            .| ...|.::     :|:.|.:.|.::|||.||:||.|:|...:||::|||..:||.|....||:
Mouse   196 RRGGGPQAIS-----IGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFL 255

  Fly   182 NNDNSTAWHDFDEGYDYESVMHYVPRAFSRN-GQPTIVPLRE--GAE-NMGQRFYMSEKDIRKLN 242
            ..:.... ....|.||::|:|||....|||. ...||||..|  |.: ::|||..:|:.||.:..
Mouse   256 KMEVQEV-ESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPSIGQRTRLSKGDIAQAR 319

  Fly   243 KMYRCP 248
            |:|:||
Mouse   320 KLYKCP 325

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Semp1NP_609756.1 ZnMc_astacin_like 55..245 CDD:239807 63/194 (32%)
Bmp1NP_033885.2 ZnMc_BMP1_TLD 126..325 CDD:239808 66/199 (33%)
CUB 327..436 CDD:395345
CUB 440..549 CDD:395345
FXa_inhibition 560..592 CDD:464251
CUB 596..705 CDD:395345
FXa_inhibition 712..747 CDD:464251
CUB 752..861 CDD:395345
CUB 865..978 CDD:395345
Blue background indicates that the domain is not in the aligned region.

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