DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Semp1 and astl

DIOPT Version :9

Sequence 1:	NP_609756.1	Gene:	Semp1 / 34914	FlyBaseID:	FBgn0028944	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_031755136.1	Gene:	astl / 101730245	XenbaseID:	XB-GENE-5769376	Length:	972	Species:	Xenopus tropicalis

Alignment Length:	240	Identity:	69/240 - (28%)
Similarity:	113/240 - (47%)	Gaps:	40/240 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 AGFYQGDI--KAHPIRTRNGIVNQIYHWP----NRTVPYMIEDDAFADSHYRE-----ILRAISI 81
            :|..:|||  :...|||.:.   :...||    :..:||.:      .|.|..     ||:|...
Frog    52 SGLMEGDIVKEKRSIRTFSA---RFAKWPKINGSVIIPYTL------SSSYESFDRNIILKAFRD 107

  Fly    82 IEENSCVIF-KPATEMDFPMALVITSKGLGCNTVHLGYRNKTQVVNLEIYPLGEGCFRI----GS 141
            ::.::|:.| :..||.|:    :.....:||      :.:..:|..:::..|...|.|.    |.
Frog   108 LQASTCLRFVERTTERDY----IAIEPAIGC------FSSVGRVGGMQLVSLAFECLRTDKGKGI 162

  Fly   142 IIHELLHVLGFEHQHVSQNRDQYVSIQWKNINPQYNINFVNNDNSTAWHDFDEGYDYESVMHYVP 206
            .:|||:||.||.|:|...:||.|:.|.|..|...|..||.    ..|..:....|:.:|::||..
Frog   163 ALHELMHVAGFWHEHSRADRDDYIWIIWDEILIGYEKNFC----KYATTNMLVKYELQSILHYPR 223

  Fly   207 RAFSRNGQPTIVPLREGAE-NMGQRFYMSEKDIRKLNKMYRCPDH 250
            .|||::||.||.|....:: .:|||..:|..||.::||:|.|..:
Frog   224 SAFSKSGQATINPKYPYSKIEIGQREKLSASDILRVNKLYSCSQY 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Semp1	NP_609756.1	Astacin	53..249	CDD:279708	62/210 (30%)
Semp1	NP_609756.1	ZnMc_astacin_like	55..245	CDD:239807	58/200 (29%)
astl	XP_031755136.1	ZnMc_astacin_like	84..263	CDD:239807	58/198 (29%)
astl	XP_031755136.1	MAM	817..971	CDD:99706
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110