DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Semp1 and accs

DIOPT Version :9

Sequence 1:	NP_609756.1	Gene:	Semp1 / 34914	FlyBaseID:	FBgn0028944	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_017948750.2	Gene:	accs / 100495810	XenbaseID:	XB-GENE-989873	Length:	492	Species:	Xenopus tropicalis

Alignment Length:	276	Identity:	80/276 - (28%)
Similarity:	125/276 - (45%)	Gaps:	53/276 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 PQIWGVIFLFTPTVFSEL----FKDPELLAGFYQGDIKAHPIRTRNGIVNQIYH----------- 52
            |.:.|.|..  |....:|    ::|.|.    |..|:.:..:::.||.|.:::.
Frog     5 PLLIGCICF--PVAVDQLPSGNYEDEEA----YHEDVFSQILKSNNGTVKKLWQGDIAIETGRSA 63

  Fly    53 -------WPNRT-----VPYMIEDDAFADSHYREILRAISIIEENSCVIF-KPATEMDFPMALVI 104
                   ||...     |||.:..| ::|:....|..|:......:||.| :.:||.||   |.|
Frog    64 TKCTSCLWPKSADGTVRVPYRLSAD-YSDNEKSSIRDALLEFNTLTCVHFVERSTEEDF---LDI 124

  Fly   105 TSKGLGCNTVHLGYRNKTQVVNLEIYPLGEGCFRIGSIIHELLHVLGFEHQHVSQNRDQYVSIQW 169
            .|.. ||.: .:|.....|.::|    :..||...|.|.||:.|.|||.|:....:||.|:.:.|
Frog   125 VSDS-GCWS-SIGRTGGAQTLSL----MSSGCLAKGIIQHEVDHALGFYHEQSRSDRDTYIDVLW 183

  Fly   170 KNI--NPQYNINFVNNDNSTAWHDFDEGYDYESVMHYVPRAFSR-NGQPTIVPLREGAENMGQRF 231
            :.|  :...:...|:.||      .|..|||.|||||...|||. :|||::.|..:...|:|||:
Frog   184 QYICESDWGSFEMVDTDN------LDLPYDYSSVMHYGWYAFSNTSGQPSLRPKPDPTANIGQRY 242

  Fly   232 YMSEKDIRKLNKMYRC 247
            .:|..|:.|:.::|.|
Frog   243 GLSPLDVSKVKELYGC 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Semp1	NP_609756.1	Astacin	53..249	CDD:279708	68/204 (33%)
Semp1	NP_609756.1	ZnMc_astacin_like	55..245	CDD:239807	64/198 (32%)
accs	XP_017948750.2	ZnMc	76..258	CDD:412141	65/197 (33%)
		CUB	261..374	CDD:238001
		CUB	377..488	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010