DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Semp1 and astl3b.4

DIOPT Version :9

Sequence 1:	NP_609756.1	Gene:	Semp1 / 34914	FlyBaseID:	FBgn0028944	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_031746772.1	Gene:	astl3b.4 / 100491283	XenbaseID:	XB-GENE-22069691	Length:	533	Species:	Xenopus tropicalis

Alignment Length:	239	Identity:	87/239 - (36%)
Similarity:	113/239 - (47%)	Gaps:	23/239 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 VFSELFK-DPELLAGFYQGDIKAHPIRTRNGIVNQIYHWPNRT-----VPYMIEDDAFADSHYRE 74
            ||:::.| :..:....|:|||.....|:.......:  ||..|     |||....:..|| ....
Frog    78 VFTQISKVNRGISVPTYEGDILRPEGRSAMNCTECL--WPKSTDGTVIVPYNFSSNYSAD-QLAL 139

  Fly    75 ILRAISIIEENSCVIFKP-ATEMDFPMALVITSKGLGCNTVHLGYRNKTQVVNLEIYPLGEGCFR 138
            ...|:...|..:||.|.| |.|..|   |.|.| |.|| ...||.....|.|.|..|    ||..
Frog   140 FKSAMQEYESLTCVRFVPRANETAF---LNIIS-GSGC-VSFLGKLGGAQTVQLASY----GCIY 195

  Fly   139 IGSIIHELLHVLGFEHQHVSQNRDQYVSIQWKNINPQYNINFVNNDNSTAWHDFDEGYDYESVMH 203
            .|.|.|||.|.|||.|:....:||.||:|..:||.|.|..||    |....::....|||.||||
Frog   196 RGIIQHELNHALGFYHEQSRSDRDDYVTIHTENILPGYEGNF----NKANTNNLGLEYDYSSVMH 256

  Fly   204 YVPRAFSRNGQPTIVPLREGAENMGQRFYMSEKDIRKLNKMYRC 247
            |...|||:||..||||..:....:|||..:|..|:.|:|::|:|
Frog   257 YPGDAFSKNGNLTIVPKPDPTVPIGQRDGLSILDVSKINRLYQC 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Semp1	NP_609756.1	Astacin	53..249	CDD:279708	79/201 (39%)
Semp1	NP_609756.1	ZnMc_astacin_like	55..245	CDD:239807	75/195 (38%)
astl3b.4	XP_031746772.1	ZnMc_hatching_enzyme	119..300	CDD:239810	75/194 (39%)
		CUB	304..412	CDD:238001
		CUB	417..525	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010