DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Semp1 and XB5949052

DIOPT Version :9

Sequence 1:	NP_609756.1	Gene:	Semp1 / 34914	FlyBaseID:	FBgn0028944	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_002932488.2	Gene:	XB5949052 / 100489456	XenbaseID:	XB-GENE-5949053	Length:	453	Species:	Xenopus tropicalis

Alignment Length:	253	Identity:	83/253 - (32%)
Similarity:	121/253 - (47%)	Gaps:	40/253 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 TVFSELF---KDPELLAGFY---QGDIKAHPIRTRNGIVNQIYHWPNRT-----VPYMIEDDAFA 68
            ::|..|:   ||.....|.|   ..||.....::.|.....|..||..:     :||:|..|.
Frog    43 SMFDRLYEVNKDALPFTGKYIVSNLDIALKLGKSANTCPKGICLWPKSSDGLVRIPYVISSDY-- 105

  Fly    69 DSHYREILRAISI--IEENSCVIFKPAT-EMDFPMALVITSKGL-GCNTVHLGYRNKTQVVNLEI 129
             |.|...|...|.  ..:.:|:...|.| |.|:     ::.:.| ||.: .:|.....|.|:::
Frog   106 -SSYSNALFQASFKGFADTTCIRLVPRTSETDY-----LSFESLNGCWS-PIGRTGGAQTVSVQ- 162

  Fly   130 YPLGEGCFRIGSIIHELLHVLGFEHQHVSQNRDQYVSIQWKNINPQYNINF----VNNDNSTAWH 190
               ..||.....|.||::|.||..|:||..:||:|||:||.||:|....||    .||.|.|.
Frog   163 ---QSGCMWTSIIEHEIIHSLGLHHEHVRSDRDKYVSVQWNNISPGNTGNFQMTDTNNMNLTK-- 222

  Fly   191 DFDEGYDYESVMHYVPRAFSRNGQ-PTIVPLREGAENMGQRFYMSEKDIRKLNKMYRC 247
                 |||.|:|||...|||.||. ||::.:.:.:.:.|..|.||:.||:|||.:|:|
Frog   223 -----YDYNSLMHYSSTAFSINGNLPTLIAVPDSSVSFGNAFMMSDLDIKKLNTLYKC 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Semp1	NP_609756.1	Astacin	53..249	CDD:279708	73/209 (35%)
Semp1	NP_609756.1	ZnMc_astacin_like	55..245	CDD:239807	69/203 (34%)
XB5949052	XP_002932488.2	ZnMc	92..275	CDD:412141	70/202 (35%)
XB5949052	XP_002932488.2	CUB	342..452	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920