DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15255 and Bmp1

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_112613.1	Gene:	Bmp1 / 83470	RGDID:	620739	Length:	990	Species:	Rattus norvegicus

Alignment Length:	317	Identity:	94/317 - (29%)
Similarity:	144/317 - (45%)	Gaps:	75/317 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VLLLQVVLNSGKPLPAGVY----------------DPEEAGGFVEGDMMLTEEQQR--NLEQGA- 54
            :|||.::..:|:||....|                ||.:|..|: ||:.|.||..|  .::|.|
  Rat    16 LLLLLLLPRAGRPLDLADYTYDLGEEDAPELLNYKDPCKAAAFL-GDIALDEEDLRAFRVQQAAV 79

  Fly    55 ----------------------------------------PKARNGLINTEKR-WPGNVVVYRIS 78
                                                    |::|....:..:| ||..|:.:.|.
  Rat    80 LRQQTAQRSSIKAAGNSSALGRQSTSGQPQRGSRGRWRSRPRSRRAATSRPERVWPDGVIPFVIG 144

  Fly    79 DDFDTAHKKAIQTGIDTLELHTCLRFREATDEDKAYLTVTAKSGGCYTAVGYQ-GAPQEMNLEIY 142
            .:|..:.:...:..:...|.|||:.|.|.|||| :|:..|.:..||.:.||.: |.||.::
  Rat   145 GNFTGSQRAVFRQAMRHWEKHTCVTFLERTDED-SYIVFTYRPCGCCSYVGRRGGGPQAIS---- 204

  Fly   143 PLGEGCFRPGTILHEFMHALGFYHQQSSSIRDDFINVIYENIVPGKEFNFQKYADTVVTDFEVGY 207
             :|:.|.:.|.::||..|.:||:|:.:...||..::::.|||.||:|:||.|.....|......|
  Rat   205 -IGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETY 268

  Fly   208 DYDSCLHYRPGAFSING--EDTIVP-LDSSAV---IGQRVGLSSKDIDKINIMYKCP 258
            |:||.:||....|| .|  .||||| .:.:.|   ||||..||..||.:...:||||
  Rat   269 DFDSIMHYARNTFS-RGIFLDTIVPKYEVNGVKPSIGQRTRLSKGDIAQARKLYKCP 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	71/199 (36%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	66/191 (35%)
Bmp1	NP_112613.1	ZnMc_BMP1_TLD	125..324	CDD:239808	71/205 (35%)
		Astacin	132..325	CDD:279708	73/200 (37%)
		CUB	326..435	CDD:278839
		CUB	439..548	CDD:278839
		FXa_inhibition	559..591	CDD:291342
		CUB	595..704	CDD:278839
		FXa_inhibition	711..746	CDD:291342
		CUB	751..860	CDD:278839
		CUB	864..977	CDD:278839
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810