DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15255 and bmp1a

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_001035126.1	Gene:	bmp1a / 572452	ZFINID:	ZDB-GENE-060818-1	Length:	986	Species:	Danio rerio

Alignment Length:	308	Identity:	92/308 - (29%)
Similarity:	139/308 - (45%)	Gaps:	70/308 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 VVLNSGKPLPAGVYDPEEAGGFVE--------------------GDMMLTEEQQR--------NL 50
            ::|:|...|.|...|..|.|.:||                    ||:.|.||..|        ||
Zfish     9 LLLSSFSLLAALDLDAIEPGYYVETSSPSDLIDYKDPCKAVAYLGDIALDEEDMRMFTVDRIVNL 73

  Fly    51 ---------------------------EQGAPKARNGLINTEKR-WPGNVVVYRISDDFDTAHKK 87
                                       .:|:.:.|....:..:| ||..|:.|.||.:|..:.:.
Zfish    74 AERTVTILNHTNTGSLSNETSVNTTASSRGSHRRRRAATSRPERVWPEGVIPYVISGNFSGSQRA 138

  Fly    88 AIQTGIDTLELHTCLRFREATDEDKAYLTVTAKSGGCYTAVGYQ-GAPQEMNLEIYPLGEGCFRP 151
            ..:..:...|.|||:.|.|.|.|: :|:..|.:..||.:.||.: |.||.::     :|:.|.:.
Zfish   139 IFRQAMRHWEKHTCVTFIERTTEE-SYIVFTYRPCGCCSYVGRRGGGPQAIS-----IGKNCDKF 197

  Fly   152 GTILHEFMHALGFYHQQSSSIRDDFINVIYENIVPGKEFNFQKYADTVVTDFEVGYDYDSCLHYR 216
            |.::||..|.:||:|:.:...||:.:::|.:||.||:|:||.|.....|......||:||.:||.
Zfish   198 GIVVHELGHVIGFWHEHTRPDRDEHVSIIRDNIQPGQEYNFLKMEPGEVDSLGEVYDFDSIMHYA 262

  Fly   217 PGAFSING--EDTIVP-LDSSAV---IGQRVGLSSKDIDKINIMYKCP 258
            ...|| .|  .|||:| .|.:.|   ||||..||..||.:...:||||
Zfish   263 RNTFS-RGIFLDTILPRYDVNGVRPPIGQRTRLSKGDIAQARKLYKCP 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	71/199 (36%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	66/191 (35%)
bmp1a	NP_001035126.1	ZnMc_BMP1_TLD	112..309	CDD:239808	71/203 (35%)
		Astacin	117..309	CDD:279708	71/198 (36%)
		CUB	311..420	CDD:278839
		CUB	424..533	CDD:278839
		FXa_inhibition	544..576	CDD:291342
		CUB	580..699	CDD:278839
		FXa_inhibition	706..741	CDD:291342
		CUB	746..855	CDD:278839
		CUB	859..972	CDD:278839
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810