DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15255 and bmp1b

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	XP_005155463.1	Gene:	bmp1b / 559877	ZFINID:	ZDB-GENE-060818-2	Length:	970	Species:	Danio rerio

Alignment Length:	276	Identity:	83/276 - (30%)
Similarity:	127/276 - (46%)	Gaps:	53/276 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 DPEEAGGFVEGDMMLTEEQQR-----------NLEQGAPK------------------------- 56
            ||.:|..|: ||:.|.||..|           |...|:.|
Zfish    36 DPCKAVAFL-GDIALDEEDLRFLKAHYMHATENESSGSSKPDSVNRSSANRNAKDEPVLANQSIL 99

  Fly    57 --ARNGLINTEKRWPGNVVVYRISDDFDTAHKKAIQTGIDTLELHTCLRFREATDEDKAYLTVTA 119
              .|......|:.||..::.|.||.:|..:.:...:..:...|.|||:.|.|.:.|: :|:..|.
Zfish   100 RRRRAATARPERVWPNGIIPYIISGNFTGSQRAIFKQAMRHWEKHTCVTFVERSVEE-SYIVFTL 163

  Fly   120 KSGGCYTAVGYQ-GAPQEMNLEIYPLGEGCFRPGTILHEFMHALGFYHQQSSSIRDDFINVIYEN 183
            :..||.:.||.: |.||.::     :|:.|.:.|.::||..|.:||:|:.:...||:.:::..||
Zfish   164 RPCGCCSFVGRRGGGPQAIS-----IGKNCDKFGIVVHELGHVIGFWHEHTRPDRDEHVDIFREN 223

  Fly   184 IVPGKEFNFQKYADTVVTDFEVGYDYDSCLHYRPGAFSING--EDTIVP-LDSSAV---IGQRVG 242
            |.||:|:||.|.....|......||:||.:||....|| .|  .||::| .|...|   ||||..
Zfish   224 IQPGQEYNFIKMEPDDVDSLGEVYDFDSIMHYARNTFS-RGIYLDTMLPKYDVDGVRPPIGQRTR 287

  Fly   243 LSSKDIDKINIMYKCP 258
            ||..||.:...:|:||
Zfish   288 LSKGDIAQARKLYRCP 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	66/198 (33%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	63/191 (33%)
bmp1b	XP_005155463.1	ZnMc_BMP1_TLD	109..303	CDD:239808	67/200 (34%)
		Astacin	111..303	CDD:279708	66/198 (33%)
		CUB	305..414	CDD:278839
		CUB	418..527	CDD:278839
		EGF_CA	530..570	CDD:214542
		CUB	575..684	CDD:278839
		FXa_inhibition	691..726	CDD:291342
		CUB	731..840	CDD:278839
		CUB	844..957	CDD:278839
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810