DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15255 and tll2l

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_001016661.1	Gene:	tll2l / 549415	XenbaseID:	XB-GENE-478930	Length:	500	Species:	Xenopus tropicalis

Alignment Length:	285	Identity:	78/285 - (27%)
Similarity:	121/285 - (42%)	Gaps:	55/285 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 YVLLLQVVLNSGKPLPA-----------GVYDPEEAGGF--------------VEGDMMLTEEQQ 47
            |:::..|...:..||..           ..:.|.:|..|              ::||:.:.
Frog     8 YIIICLVTYATSLPLTTLEKPLESDDHQETHKPNDADIFTQIIASNEGIDQLLLQGDIAIR---- 68

  Fly    48 RNLEQGAPKARNGLINTEKRWP----GNV-VVYRISDDFDTAHKKAIQTGIDTLELHTCLRFREA 107
                    ..|:.|.....:|.    |.| |.:.:|..:..:....|...:...|..||:.|...
Frog    69 --------VVRSSLQCDNCKWDISSNGKVPVPFTVSPGYTKSQLALITAAMQEFETLTCVDFVPK 125

  Fly   108 TDEDKAYLTVTAKSGGCYTAVGYQGAPQEMNLEIYPLGEGCFRPGTILHEFMHALGFYHQQSSSI 172
            |:| |..:.:. ...||::.:|..|..|:::|.    .:.|...|.|.||..|.|||.|:...|.
Frog   126 TNE-KNVININ-NGNGCWSYIGRSGGVQQVSLS----KQSCMVKGIIQHELNHVLGFVHEHVRSD 184

  Fly   173 RDDFINVIYENIVPGKEFNFQKYADTVVT-DFEVGYDYDSCLHYRPGAFSING--EDTIVPLDSS 234
            ||.::||:.:||:|....||    |..|| :..:.|||.|.:||...||||:.  ...|...|.:
Frog   185 RDQYVNVVKKNILPDSLGNF----DIAVTNNLGLPYDYYSVMHYPRNAFSISPFLPTLITKPDPT 245

  Fly   235 AVIGQRVGLSSKDIDKINIMYKCPI 259
            ..||||.||::.||.|||.:|.|.:
Frog   246 IQIGQRYGLTNLDIAKINKLYNCDV 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	66/199 (33%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	64/188 (34%)
tll2l	NP_001016661.1	ZnMc_hatching_enzyme	86..268	CDD:239810	65/191 (34%)
		CUB	272..382	CDD:238001
		CUB	385..495	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020