DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15255 and mep1a

DIOPT Version :9

Sequence 1:	NP_001285958.1	Gene:	CG15255 / 34913	FlyBaseID:	FBgn0028950	Length:	261	Species:	Drosophila melanogaster
Sequence 2:	NP_001015767.1	Gene:	mep1a / 548484	XenbaseID:	XB-GENE-921661	Length:	704	Species:	Xenopus tropicalis

Alignment Length:	281	Identity:	89/281 - (31%)
Similarity:	134/281 - (47%)	Gaps:	45/281 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSRSGI--------IYVLLLQVVLN----SGKPLPAGVYDPE------EAG-GFVEGDMMLTEEQ 46
            |.|.|:        :.|.|..:.:|    .|....||....:      |:| ...|||::|
Frog     1 MGRQGLFRLCCLLGLSVCLTAISINHRPKQGNEADAGELREDIPQINLESGLNLFEGDIVL---- 61

  Fly    47 QRNLEQGAPKARNGLINTEKRW--PGNVVVYRISDDFDTAHKKAIQTGIDTLELHTCLRFREATD 109
                   .|:|||.|::...||  |   :.|.::|:.|...|..|....:...|.:|:.|:....
Frog    62 -------PPRARNALLDDYYRWSFP---IPYILADNLDLNAKSVILKAFEMFRLKSCVDFKPYEG 116

  Fly   110 EDKAYLTVTAKSGGCYTAVGYQGAPQEMNLEIYPLGEGCFRPGTILHEFMHALGFYHQQSSSIRD 174
            | ..|:.. .|.|||::.||.....|.::     :||.|.....:.||.:|||||||:||.|.||
Frog   117 E-PTYIHF-QKFGGCWSMVGDLKVGQNLS-----IGERCDYKAIVEHEILHALGFYHEQSRSDRD 174

  Fly   175 DFINVIYENIVPGKEFNFQKYADTVVTDFEVGYDYDSCLHYRPGAFSINGEDTIVPLDSSA---V 236
            |::.:.:|.|..|.|.||.||.|..:||....|||:|.:||.|.:|:.|.:...:.....|   :
Frog   175 DYVKIWWEEITSGMEHNFNKYEDNYITDLNTPYDYESVMHYGPLSFNKNPDVPTITAKIEAFNDI 239

  Fly   237 IGQRVGLSSKDIDKINIMYKC 257
            ||||:..|..|::::|.||.|
Frog   240 IGQRLDFSEIDLERLNRMYNC 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15255	NP_001285958.1	Astacin	66..258	CDD:279708	69/197 (35%)
CG15255	NP_001285958.1	ZnMc_astacin_like	70..255	CDD:239807	63/187 (34%)
mep1a	NP_001015767.1	ZnMc_meprin	31..260	CDD:239809	82/249 (33%)
		MAM	270..431	CDD:366209
		MATH_Meprin_Alpha	430..596	CDD:239752
		EGF	635..>658	CDD:333761
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	145	1.000	Domainoid score	I4540
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X245
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.100